NeuroMab™ Anti-IGF1R BBB Shuttle Antibody, Clone h7C10
- Host Species:
- Humanized
- Species Reactivity:
- Human
- Applications:
- FC; Inhib; In Vivo; In Vitro
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Notes: The BBB antibody is made-to order and available in a customized format. Please don't hesitate contact us for more details.
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Figure 1 In vivo effects of monoclonal antibody 7C10 on MCF-7 tumor growth in nude mice.
Figure 2 Comparative study of the effects of MAb 7C10 and tamoxifen on the growth of tumor MCF-7 in vivo.
Figure 3 Anti-tumor activity of mouse antibody 7C10 in tumor cell xenograft model in vivo.
Figure 4 Antitumor effect study of MAb 7C10 compared with vinorelbine (vinorelbine), and the synergistic effect of the two compounds on the growth of A549 line in vivo.
Figure 5 Comparison of mouse 7C10 and chimeric C7C10 MAbs inhibiting IGF1 proliferation in MCF-7 cells in vitro. Antibody 9G4 is a murine IgG1 isotype used as an experimental control.
Figure 6 Effect of 7C10 and h7C10 MAbs (Humanized 1, written here as 7H2HM) on IGF1-induced signaling.
Figure 7. Comparative effects of 7C10 and h7C10 MAbs (humanized 1, written here as 7H2HM) on an in vitro model of IGF1-induced proliferation of MCF-7 cells.
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