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Creative Biolabs
Product

NeuroMab™ Anti-Leptin Antibody,Clone NR2960P

[CAT#: NRP-0422-P1628]

Functional antibody against Human Leptin

Host Species:
Human
Species Reactivity:
Human
Applications:
ELISA; Neut; IHC; In Vitro; In Vivo

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Product Overview

Description

The anti-leptin monoclonal antibody is screened by using in-house prepared scFv phage display human antibody library. The antibody increases leptin transcription in brown and epididymal adipose tissue, reduces circulating leptin, and reduces high fat diet effects on brown adipose tissue.

Species Reactivity

Human

Clonality

Monoclonal

Host Species

Human

Clone Number

NR2960P

Applications

ELISA; Neut; IHC; In Vitro; In Vivo

Relevant Diseases

Alzheimer's Disease; Obesity
Product Properties

Formulation

PBS only

Preservatives

BSA Free

Concentration

1mg/mL

Purification

Purified recombinant IgG prepared by affinity chromatography on Protein A from a mammalian cell line

Purity

> 95% (SDS-PAGE)

Endotoxin Level

Regular Endotoxin < 5 EU/mg
Low Endotoxin < 1 EU/mg

Shipping

Gel Packs

Storage

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Research Use Only

For research use only
Target

Target

Leptin

Official Name

LEP

Full Name

Leptin

Alternative Names

LEP; LEPD; OB; OBS; leptin

Gene ID

3952(Human); 16846(Mouse); 25608(Rat)

Uniprot ID

P41159(Human); P41160(Mouse); P50596(Rat)
Product Pictures
FuncS

Figure 1. Antibody therapy reduces body weight.

FuncS

figure 2. Antibody therapy reduces food intake.

FuncS

Figure 3. Antibody therapy increases leptin transcription in brown and epididymal adipose tissue.

FuncS

Figure 4. Antibody therapy reduces circulating leptin.

FuncS

Figure 5. Antibody treatment reduces the effect of a high-fat diet on brown adipose tissue.

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