NeuroMab™ Anti-HMGB1 Antibody,Clone NR2803P
Functional antibody against Human HMG1
- Host Species:
- Human
- Species Reactivity:
- Human
- Applications:
- ELISA; Inhib; In Vitro; In Vivo
To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
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SPECIFIC INQUIRY
inquiryDescription
Species Reactivity
Clonality
Host Species
Clone Number
Applications
Relevant Diseases
Formulation
Preservatives
Concentration
Purification
Purity
Endotoxin Level
Low Endotoxin < 1 EU/mg
Shipping
Storage
Research Use Only
Figure 1 Binding kinetics and specificity of human anti-HMG1 antibodies.
HMG1 capture ELISA binding curves of several human anti-HMG1 antibodies demonstrate that these antibodies have different affinities for recombinant HMG1 produced in E. coli.
Figure 2 A number of human anti-HMG1 antibodies inhibited HMG1-stimulated cytokine release from human PBMCs.
Figure 3 Several human anti-HMG1 antibodies inhibit HMG1-stimulated cytokine gene expression in mouse macrophages (mMO).
Figure 4. A subset of human anti-HMG1 antibodies block the binding of recombinant HMG1 to RAGE.
Figure 5 HMG1 staining pattern in human brain tissue from multiple sclerosis (MS) specimens.
Specific HMGB1 staining of the cytoplasm of the microglia and the interstitia of an MS Plaque with Activated Microglia using 1 μg/ml G16.
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