NeuroMab™ Anti-HMGB1 Antibody,Clone NR3790P
- Host Species:
- Humanized
- Species Reactivity:
- Human; Mouse
- Applications:
- ELISA; WB; IF; Inhib; In Vitro; In Vivo
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SPECIFIC INQUIRY
inquiryDescription
Species Reactivity
Clonality
Host Species
Clone Number
Applications
Relevant Diseases
Preservatives
Concentration
Endotoxin Level
Low Endotoxin < 1 EU/mg
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Research Use Only
Figure 1 Binding kinetics and specificity of human anti-HMG1 antibodies.
HMG1 capture ELISA binding curves of several human anti-HMG1 antibodies demonstrate that these antibodies have different affinities for recombinant HMG1 produced in E. coli.
Figure 2 A number of human anti-HMG1 antibodies inhibited HMG1-stimulated cytokine release from human PBMCs.
Figure 3 Several human anti-HMG1 antibodies inhibit HMG1-stimulated cytokine gene expression in mouse macrophages (mMO).
Figure 4. A subset of human anti-HMG1 antibodies block the binding of recombinant HMG1 to RAGE.
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