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Creative Biolabs
Product

Human P2RY2 β-Arrestin GPCR Cell Line [U2OS]

[CAT#: NCL-7P991]

Species:
Human
Applications:
GPCR Screening
Cell Types:
GPCR Cell

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Product Overview

Description

The β-Arrestin GPCR cell line NCL-7P991 at Creative Biolabs is engineered to co-express PK-labeled GPCR and enzyme receptor (EA) labeled β-Arrestin. Activation of GPCR-PK induces the recruitment of β-Arrestin-EA, forcing the two enzyme fragments to complement each other.

Features

Coupling: Gq
β-Arrestin isoform: β-Arrestin-2
Tag: PK1
Agonist/Ligand: Uridine 5'-Triphosphate

Cell Types

GPCR Cell

Cell Location

β-Arrestin

Applications

GPCR Screening

Assay

GPCR Screening Assay

Readout

β-Arrestin

Assay Characteristics

Coupling: Gq
β-Arrestin isoform: β-Arrestin-2
Tag: PK1
Agonist/Ligand: Uridine 5'-Triphosphate

Species

Human
Properties

Shipping

Dry ice.

Storage

Liquid Nitrogen

Research Use Only

For research use only

Quality Control

All cells test negative for mycoplasma, bacteria, yeast, and fungi.
Target Details

Target

P2RY2

Official Name

P2RY2

Alternative Names

ADP-glucose receptor; ADPG-R; BDPLT8; G-protein coupled receptor SP1999; Gi-coupled ADP receptor HORK3; HORK3; P2T(AC); P2Y purinoceptor 12; P2Y(AC); P2Y(ADP); P2Y(cyc); P2Y12; P2Y12 platelet ADP receptor; SP1999; purinergic receptor P2RY12; purinergic receptor P2Y; G-protein coupled; 12; putative G-protein coupled receptor
Publications

Publications (0)

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For Research Use Only. Not For Clinical Use.
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