Proteins & Peptides
Proteins and peptides are macromolecules that perform a multitude of vital functions, many of which are indispensable to life. These include cytokines, neurotrophins, growth factors, signaling proteins, viral and bacterial antigens, human immunoglobulins, and numerous other biological entities. With a wealth of knowledge in the field of neuroscience, we are certain that we can offer you a wide range of affordable, high-quality neuroproteins and peptides to help you expedite your drug development efforts for neurological disease targets.
Applications
- Physiological & Pathological Research
The causal relationship between pathogenic mutations and increased protein aggregation is a key feature of neurodegenerative diseases, such as those encoding amyloid precursor protein (AD), tau protein (AD), alpha-synuclein (PD), etc. We are delighted to provide a variety of active recombinant proteins for neurodegenerative disease research, assisting you to discover ways to prevent protein aggregation, facilitate precipitate clearance, or induce their recovery.
- In Vitro Modeling
Chronic neuroinflammation has been linked to the advancement of neurodegenerative disorders like Alzheimer's disease (AD), Parkinson's disease (PD), amyotrophic lateral sclerosis (ALS), and multiple sclerosis (MS). Cytokines are a common stimulus that induces inflammation and can be employed to induce in vitro neuroinflammatory models. Cytokines activate related receptors, thereby initiating key intracellular signaling pathways. The following cytokines have been identified as key stimuli in neuroinflammatory processes: IFN-γ, IL-33, TNF-α, IL-1β, and IL-6.
- Enzyme Assay
Enzymes are essential proteins crucial for chemical processes and are employed extensively in the development of pharmaceuticals and biological research. Our product list contains a variety of proteins that can be used to initiate enzyme signaling, including from a variety of animal sources.
BBB Shuttle Proteins
Transcytosis is a phenomenon that occurs in a multitude of cell types. At Creative Biolabs, we employ receptor-mediated transcytosis (RMT) to develop engineered carriers (BBB shuttle proteins) to improve blood-brain barrier (BBB) crossing. The protein-based engineered carrier is expected to significantly enhance the ability of macromolecules to reach the brain, thereby accelerating central nervous system disease research.
Fig.1 Receptor-mediated transcytosis engineered BBB shuttle proteins.1
If the product you're looking for isn't listed, please contact us immediately. Our reagent experts will assist you in selecting the right product for your specific application. Kindly reach out to us via phone or email, and we will be happy to help you locate the ideal product for the task.
Reference
- Pulgar, Victor M. "Transcytosis to cross the blood brain barrier, new advancements and challenges." Frontiers in neuroscience 12 (2019): 418903. Distributed under Open Access license CC BY 4.0, without modification.



- Species:
- Human
- Relevant Diseases:
- Neuroinflammation


- Species:
- Human
- Relevant Diseases:
- Parkinson's Disease


- Species:
- Human


- Species:
- Human
- Relevant Diseases:
- Atherosclerosis


- Species:
- Human
- Relevant Diseases:
- MPSIIIB


- Species:
- Human
- Relevant Diseases:
- Sanfilippo type A syndrome


- Species:
- Human
- Relevant Diseases:
- MLD


- Species:
- Human
- Relevant Diseases:
- Hunter's syndrome


- Species:
- Human


- Species:
- Human
- Relevant Diseases:
- Neuroinflammation


- Species:
- Human
- Relevant Diseases:
- Parkinson's Disease


- Species:
- Human


- Species:
- Human
- Relevant Diseases:
- Hurler's syndrome


- Species:
- Human
- Relevant Diseases:
- LSDs
- iNeuMab™ Anti-ApoC3 BBB Shuttle Antibody (NRZP-1022-ZP3505) (Cat#: NRZP-1022-ZP3505)
- iNeuMab™ Anti-SEZ6 Antibody (NRP-0422-P517) (Cat#: NRP-0422-P517)
- iNeuMab™ Anti-Tau Antibody (NRP-0422-P1684) (Cat#: NRP-0422-P1684)
- iNeuMab™ Anti-Tau Antibody (NRP-0422-P1760) (Cat#: NRP-0422-P1760)
- iNeuMab™ Anti-TNFα BBB Shuttle Antibody (NRZP-1022-ZP4105) (Cat#: NRZP-1022-ZP4105)
- iNeuMab™ Anti-pTau Antibody (NRP-0422-P1719) (Cat#: NRP-0422-P1719)
- iNeuMab™ Anti-GARP Antibody (NRP-0422-P1639) (Cat#: NRP-0422-P1639)
- iNeuMab™ Mouse Anti-LRP1 Monoclonal Antibody (CBP3363) (Cat#: NAB-0720-Z6479)
- iNeuMab™ Anti-Amyloid Beta 1-15 Antibody (NRP-0422-P867) (Cat#: NRP-0422-P867)
- iNeuMab™ Mouse Anti-EFNB2 Monoclonal Antibody (CBP1159) (Cat#: NAB-0720-Z4396)
- Mouse Retinal Ganglion Cells (Cat#: NCL2110P145)
- Human Retinal Epithelial Cell ARPE-19 (Cat#: NCL2110P069)
- Mouse Glioma Cell Line GL-261-Luc (Cat#: NCL-2108P06)
- iNeu™ Human Schwann Cell (Cat#: NCL-2103-P63)
- Human Brain Vascular Adventitial Fibroblasts (Cat#: NCL-21P6-014)
- Mouse Glioma Cell Line GL261-GFP (Cat#: NCL-2108P04)
- Human Glial (Oligodendrocytic) Hybrid Cell Line (MO3.13) (Cat#: NCL-2108P34)
- Mouse Retinal Ganglion Cell Line RGC-5 (Cat#: NCL2110P154)
- Human Astrocytes (Cat#: NCC20-9PZ01)
- Human Microglia Cell Line HMC3, Immortalized (Cat#: NCL-2108P38)
- Alpha-Synuclein Aggregation Assay Kit (Cat#: NRZP-1122-ZP37)
- Alpha Synuclein Aggregation Kit (Cat#: NRZP-1122-ZP15)
- Human GFAP ELISA Kit [Colorimetric] (Cat#: NPP2011ZP383)
- Amyloid beta 1-42 Kit (Cat#: NRP-0322-P2170)
- Beta Amyloid (1-42), Aggregation Kit (Cat#: NRZP-0323-ZP200)
- Beta Amyloid (1-40), Aggregation Kit (Cat#: NRZP-0323-ZP199)
- Human Poly ADP ribose polymerase,PARP Assay Kit (Cat#: NRZP-1122-ZP62)
- Human Tau Aggregation Kit (Cat#: NRP-0322-P2173)
- VSV-eGFP (Cat#: NTA-2011-ZP20)
- AAV2 Full Capsids, Reference Standards (Cat#: NTC2101070CR)
- Dextran, NHS Activated (Cat#: NRZP-0722-ZP124)
- Human superoxide dismutase 1, soluble (SOD1) (NM_000454) ORF clone, TurboGFP Tagged (Cat#: NEP-0521-R0748)
- Mouse SOD1 shRNA Silencing Adenovirus (Cat#: NV-2106-P14)
- Human huntingtin (HTT) (NM_002111) ORF clone, Myc-DDK Tagged (Cat#: NEP-0521-R0497)
- Human superoxide dismutase 3, extracellular (SOD3) (NM_003102) ORF clone, Untagged (Cat#: NEP-0521-R0808)
- App Rat amyloid beta (A4) precursor protein (App)(NM_019288) ORF clone, Untagged (Cat#: NEP-0421-R0053)
- Human apolipoprotein E (APOE) (NM_000041) ORF clone, Untagged (Cat#: NEP-0421-R0232)
- Tau Antisense Oligonucleotide (IONIS-MAPTRx) (Cat#: NV-2106-P29)
- Human presenilin 1 (PSEN1), transcript variant 2 (NM_007318) ORF clone, TurboGFP Tagged (Cat#: NEP-0421-R0140)
- Mouse Parkinson disease (autosomal recessive, early onset) 7 (Park7) (NM_020569) clone, Untagged (Cat#: NEP-0621-R0133)
- Human huntingtin-associated protein 1 (HAP1) transcript variant 2 (NM_177977) ORF clone, Myc-DDK Tagged (Cat#: NEP-0521-R0676)
- NeuroBiologics™ Monkey Cerebrospinal Fluid (Cat#: NRZP-0822-ZP495)
- NeuroBiologics™ Rat Cerebrospinal Fluid (Cat#: NRZP-0822-ZP496)
- NeuroBiologics™ Human Cerebrospinal Fluid (Cat#: NRZP-0822-ZP491)
- NeuroBiologics™ Mouse Cerebrospinal Fluid (Cat#: NRZP-0822-ZP497)
- NeuroBiologics™ Pig Cerebrospinal Fluid (Cat#: NRZP-0822-ZP498)
- NeuroPro™ Anti-GDNF BBB Shuttle Protein (Cat#: NRZP-0423-ZP509)
- NeuroPro™ Anti-ASA BBB Shuttle Protein (Cat#: NRZP-0423-ZP504)
- NeuroPro™ Anti-EPO BBB Shuttle Protein (Cat#: NRZP-0423-ZP508)
- NeuroPro™ Anti-GDNF BBB Shuttle Protein (Cat#: NRZP-0423-ZP500)
- NeuroPro™ Anti-IDUA BBB Shuttle Protein (Cat#: NRZP-0423-ZP498)
- NeuroPro™ Anti-SGSH BBB Shuttle Protein (Cat#: NRZP-0423-ZP505)
- NeuroPro™ Anti-TNFR BBB Shuttle Protein (Cat#: NRZP-0423-ZP510)
- NeuroPro™ Anti-idursulfase BBB Shuttle Protein (Cat#: NRZP-0423-ZP497)
- NeuroPro™ Anti-IDUA BBB Shuttle Protein (Cat#: NRZP-0423-ZP502)
- NeuroPro™ Anti-PON1 BBB Shuttle Protein (Cat#: NRZP-0423-ZP507)