Viral Tracer Tools
Non-viral conventional tracers are effective tools for visualizing a large number of neural connections. The only specified parameter is the position of the cell body or axon end. They usually come in a form that is easy to inject and can be tested in any target animal because they do not require specific genetically modified strains or genetic methods. However, the use of non-viral conventional tracers is mainly limited to mapping global connections. Most conventional tracers do not have sufficient resolution to reveal connectivity at the level of molecularly defined cell types. They also did not reveal whether axons that terminate in specific locations are in contact with specific cell types or synapses connected to other cells. Conventional tracers can remain outside the cells at the injection site, and they usually mark the injection site or all cell bodies projected at the injection site.
Instead, genetic strategies can be used to target viruses to specific cell types, for example, through specific expression of viral receptors or through expression of recombinase proteins in specific cells to direct productive infection or payload delivery to these cells. In some cases, the virus can be modified to express a small molecule tracer in the target cell type of interest.
Creative Biolabs offers a variety of viral vectors to replace chemical tracers with targeted viral genetics methods.
Table 1: Properties of
Commonly Used Transneuronal/Trans-synaptic Viral Tracers.
Please don’t hesitate to contact us for more details.
Loading...
rAAV-E-SARE-Cre-ERT2-PEST-WPRE-hGH polyA [CAT#: NTA-2010-TT342]
- Tracer Type:
- Recombinase
- Applications:
- Recombinase
VSV-eGFP [CAT#: NTA-2011-ZP20]
Anterograde, multisynaptic
- Tracer Type:
- Anterograde tracing virus
- Applications:
- Neural Tracing
- Tracer Type:
- Tetracycline System
- Applications:
- Neural Tracing
- Tracer Type:
- Fluorescent labeling
- Applications:
- Multi-signature neuronal labeling; IBIST
- Tracer Type:
- Fluorescent labeling
- Applications:
- Multi-signature neuronal labeling; IBIST
- Tracer Type:
- Fluorescent labeling
- Applications:
- Multi-signature neuronal labeling; IBIST
Custom Vector Development Service
- Tracer Type:
- Neurotransmitter sensor
- Applications:
- cAMP Indicator
Custom Vector Development Service
- Tracer Type:
- Fluorescent labeling
Custom Vector Development Service
- Tracer Type:
- Fluorescent labeling
Custom Vector Development Service
- Tracer Type:
- Neurotransmitter sensor
Fluorescent probe
GRAB peptide sensors for detecting corticotropin-releasing factor.
- Tracer Type:
- Neurotransmitter sensor
- Applications:
- CRH Sensor
- Tracer Type:
- Neurotransmitter sensor
- Applications:
- Neurotransmitter Sensor
Fluorescent probe
GRAB peptide sensors for detecting somatostatin.
- Tracer Type:
- Neurotransmitter sensor
- Applications:
- Somatostatin Sensor
- Tracer Type:
- Neurotransmitter sensor
- Applications:
- Endocannabinoid Sensor
- Tracer Type:
- Neurotransmitter sensor
- Applications:
- Neurotransmitter Sensor
- Tracer Type:
- Neurotransmitter sensor
- Applications:
- ATP Sensor
- Tracer Type:
- Neurotransmitter Sensor
- Applications:
- Orexin Sensor
- Tracer Type:
- Neurotransmitter Sensor
- Applications:
- Orexin Sensor
- Tracer Type:
- Neurotransmitter sensor
- Applications:
- Neurotransmitter Sensor
- Tracer Type:
- Neurotransmitter sensor
- Applications:
- Neurotransmitter Sensor
- Tracer Type:
- Neurotransmitter sensor
- Applications:
- Glutamate Sensor
- Tracer Type:
- Neurotransmitter sensor
- Applications:
- GABA Sensor
- Tracer Type:
- Neurotransmitter sensor
- Applications:
- CRH Sensor
- Tracer Type:
- Neurotransmitter sensor
- Applications:
- Acetylcholine Sensor
- Tracer Type:
- Neurotransmitter sensor
- Applications:
- Dopamine Sensor
- Tracer Type:
- Neurotransmitter sensor
- Applications:
- Dopamine Sensor
Fluorescent probe
Ready-to-use AAV particles
- Tracer Type:
- Fluorescent labeling
- Applications:
- Neurotransmitter Sensor
Fluorescent probe
Ready-to-use AAV particles
- Tracer Type:
- Fluorescent labeling
- Applications:
- Neurotransmitter Sensor
- Tracer Type:
- Neurotransmitter sensor
- Applications:
- GABA Sensor
- Tracer Type:
- Neurotransmitter sensor
- Applications:
- Glutamate Sensor
- iNeuMab™ Mouse Anti-EFNB2 Monoclonal Antibody (CBP1159) (Cat#: NAB-0720-Z4396)
- NeuroMab™ Anti-SEZ6 Antibody(NRP-0422-P517) (Cat#: NRP-0422-P517)
- NeuroMab™ Anti-Alpha Synuclein Antibody(NRP-0422-P614) (Cat#: NRP-0422-P614)
- NeuroMab™ Anti-CD32b Antibody(NRP-0422-P1803) (Cat#: NRP-0422-P1803)
- NeuroMab™ Anti-GARP Antibody(NRP-0422-P1639) (Cat#: NRP-0422-P1639)
- NeuroMab™ Anti-SEZ6 Antibody(NRP-0422-P515) (Cat#: NRP-0422-P515)
- NeuroMab™ Anti-TREM2 Antibody(NRP-0422-P792) (Cat#: NRP-0422-P792)
- NeuroMab™ Anti-Amyloid Beta 1-15 Antibody(NRP-0422-P867) (Cat#: NRP-0422-P867)
- NeuroMab™ Anti-CD20 Antibody(NRP-0422-P1230) (Cat#: NRP-0422-P1230)
- NeuroMab™ Anti-EPHB2 Antibody(NRP-0422-P1220) (Cat#: NRP-0422-P1220)
- Human Microglia Cell Line HMC3, Immortalized (Cat#: NCL-2108P38)
- Human Brain Vascular Adventitial Fibroblasts (Cat#: NCL-21P6-014)
- Rat Olfactory Ensheathing Cells (Cat#: NRZP-1122-ZP162)
- Human Retinal Epithelial Cell ARPE-19 (Cat#: NCL2110P069)
- iNeu™ Human Sensory Neurons (Cat#: NCL-2103-P62)
- Mouse Midbrain Dopaminergic Neuron Cell MN9D (Cat#: NCL2110P059)
- Rat Schwann Cells RSC96, Immortalized (Cat#: NCL-2108P21)
- iNeu™ Human Oligodendrocyte Progenitor Cells (OPCs) (Cat#: NCL-2103-P49)
- Mouse Microglia Cell Line BV-2, Immortalized (Cat#: NCL2110P153)
- Human Astrocytes (Cat#: NCC20-9PZ01)
- Alpha Synuclein Aggregation Kit (Cat#: NRZP-1122-ZP15)
- Human GFAP ELISA Kit [Colorimetric] (Cat#: NPP2011ZP383)
- Beta Amyloid (1-40), Aggregation Kit (Cat#: NRZP-0323-ZP199)
- Amyloid beta 1-42 Kit (Cat#: NRP-0322-P2170)
- Alpha-Synuclein Aggregation Assay Kit (Cat#: NRZP-1122-ZP37)
- Beta Amyloid (1-42), Aggregation Kit (Cat#: NRZP-0323-ZP200)
- Human Poly ADP ribose polymerase,PARP Assay Kit (Cat#: NRZP-1122-ZP62)
- Human Tau Aggregation Kit (Cat#: NRP-0322-P2173)
- pAAV-syn-jGCaMP8s-WPRE (Cat#: NTA-2106-P063)
- Dextran, NHS Activated, 40 kDa (Cat#: NRZP-0722-ZP124)
- pAAV-syn-FLEX-jGCaMP8m-WPRE (Cat#: NTA-2106-P065)
- pAAV-syn-jGCaMP8m-WPRE (Cat#: NTA-2106-P062)
- VSV-eGFP (Cat#: NTA-2011-ZP20)
- pAAV-hSyn-DIO-XCaMP-R-WPRE (Cat#: NTA-2012AD-P508)
- rAAV-E-SARE-Cre-ERT2-PEST-WPRE-hGH polyA (Cat#: NTA-2010-TT342)
- pAAV-syn-jGCaMP8f-WPRE (Cat#: NTA-2106-P061)
- pAAV-syn-FLEX-jGCaMP8s-WPRE (Cat#: NTA-2106-P066)
- Dextran-FITC (Cat#: NTA-2011-ZP110)
- Mouse SOD1 shRNA Silencing Adenovirus (Cat#: NV-2106-P14)
- App Rat amyloid beta (A4) precursor protein (App)(NM_019288) ORF clone, Untagged (Cat#: NEP-0421-R0053)
- Human presenilin 1 (PSEN1), transcript variant 2 (NM_007318) ORF clone, TurboGFP Tagged (Cat#: NEP-0421-R0140)
- Human huntingtin-associated protein 1 (HAP1) transcript variant 2 (NM_177977) ORF clone, Myc-DDK Tagged (Cat#: NEP-0521-R0676)
- Rat Parkinson disease (autosomal recessive, juvenile) 2, parkin (Park2) (NM_020093) ORF clone/lentiviral particle, Myc-DDK Tagged (Cat#: NEP-0621-R0041)
- Human apolipoprotein E (APOE) (NM_000041) ORF clone, Untagged (Cat#: NEP-0421-R0232)
- Human superoxide dismutase 1, soluble (SOD1) (NM_000454) ORF clone, TurboGFP Tagged (Cat#: NEP-0521-R0748)
- Lenti of Human TAR DNA binding protein (TARDBP) (NM_007375) ORF clone, mGFP Tagged (Cat#: NEP-0521-R0832)
- ABCA1 Antisense Oligonucleotide (NV-2106-P27) (Cat#: NV-2106-P27)
- Human superoxide dismutase 3, extracellular (SOD3) (NM_003102) ORF clone, Untagged (Cat#: NEP-0521-R0808)
- NeuroBiologics™ Mouse Cerebrospinal Fluid (Cat#: NRZP-0822-ZP497)
- NeuroBiologics™ Monkey Cerebrospinal Fluid (Cat#: NRZP-0822-ZP495)
- NeuroBiologics™ Rat Cerebrospinal Fluid (Cat#: NRZP-0822-ZP496)
- NeuroBiologics™ Human Cerebrospinal Fluid (Cat#: NRZP-0822-ZP491)
- NeuroBiologics™ Pig Cerebrospinal Fluid (Cat#: NRZP-0822-ZP498)
- NeuroPro™ Anti-idursulfase BBB Shuttle Protein (Cat#: NRZP-0423-ZP497)
- NeuroPro™ Anti-IDS BBB Shuttle Protein (Cat#: NRZP-0423-ZP503)
- NeuroPro™ Anti-ASA BBB Shuttle Protein (Cat#: NRZP-0423-ZP504)
- NeuroPro™ Anti-GDNF BBB Shuttle Protein (Cat#: NRZP-0423-ZP500)
- NeuroPro™ Anti-TNFR BBB Shuttle Protein (Cat#: NRZP-0423-ZP510)
- NeuroPro™ Anti-EPO BBB Shuttle Protein (Cat#: NRZP-0423-ZP508)
- NeuroPro™ Anti-GDNF BBB Shuttle Protein (Cat#: NRZP-0423-ZP509)
- NeuroPro™ Anti-NAGLU BBB Shuttle Protein (Cat#: NRZP-0423-ZP506)
- NeuroPro™ Anti-TNFR BBB Shuttle Protein (Cat#: NRZP-0423-ZP501)
- NeuroPro™ Anti-SGSH BBB Shuttle Protein (Cat#: NRZP-0423-ZP505)
