Viral Tracer Tools
Non-viral conventional tracers are effective tools for visualizing a large number of neural connections. The only specified parameter is the position of the cell body or axon end. They usually come in a form that is easy to inject and can be tested in any target animal because they do not require specific genetically modified strains or genetic methods. However, the use of non-viral conventional tracers is mainly limited to mapping global connections. Most conventional tracers do not have sufficient resolution to reveal connectivity at the level of molecularly defined cell types. They also did not reveal whether axons that terminate in specific locations are in contact with specific cell types or synapses connected to other cells. Conventional tracers can remain outside the cells at the injection site, and they usually mark the injection site or all cell bodies projected at the injection site.
Instead, genetic strategies can be used to target viruses to specific cell types, for example, through specific expression of viral receptors or through expression of recombinase proteins in specific cells to direct productive infection or payload delivery to these cells. In some cases, the virus can be modified to express a small molecule tracer in the target cell type of interest.
Creative Biolabs offers a variety of viral vectors to replace chemical tracers with targeted viral genetics methods.
Table 1: Properties of
Commonly Used Transneuronal/Trans-synaptic Viral Tracers.
Please don’t hesitate to contact us for more details.
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VSV-eGFP [CAT#: NTA-2011-ZP20]
- Tracer Type:
- Anterograde tracing virus
- Applications:
- Neural Tracing
- Tracer Type:
- Fluorescent labeling
- Applications:
- Multi-signature neuronal labeling; IBIST
- Tracer Type:
- Fluorescent labeling
- Applications:
- Multi-signature neuronal labeling; IBIST
- Tracer Type:
- Fluorescent labeling
- Applications:
- Multi-signature neuronal labeling; IBIST
Custom Vector Development Service
- Tracer Type:
- Fluorescent labeling
Custom Vector Development Service
- Tracer Type:
- Fluorescent labeling
- Tracer Type:
- Neurotransmitter sensor
- Applications:
- Neurotransmitter Sensor
Fluorescent probe
- Tracer Type:
- Neurotransmitter sensor
- Applications:
- ATP Sensor
- Tracer Type:
- Neurotransmitter sensor
- Applications:
- Neurotransmitter Sensor
- Tracer Type:
- Neurotransmitter sensor
- Applications:
- Neurotransmitter Sensor
- Tracer Type:
- Neurotransmitter sensor
- Applications:
- Acetylcholine Sensor
- Tracer Type:
- Neurotransmitter sensor
- Applications:
- Neurotransmitter Sensor
Fluorescent probe
- Tracer Type:
- Neurotransmitter sensor
- Applications:
- Acetylcholine Sensor
- Tracer Type:
- Neurotransmitter sensor
- Applications:
- Oxytocin Sensor
- Tracer Type:
- Neurotransmitter sensor
- Applications:
- Oxytocin Sensor
- Tracer Type:
- Neurotransmitter Sensor
- Applications:
- Neurotransmitter Sensor
- Tracer Type:
- Neurotransmitter Sensor
- Applications:
- Neurotransmitter Sensor
- Tracer Type:
- Neurotransmitter sensor
- Applications:
- Adenosine Sensor
Fluorescent probe
- Tracer Type:
- Neurotransmitter sensor
- Applications:
- Acetylcholine Sensor
Fluorescent probe
- Tracer Type:
- Neurotransmitter sensor
- Applications:
- Acetylcholine Sensor
- Tracer Type:
- Neurotransmitter sensor
- Applications:
- Acetylcholine Sensor
Fluorescent probe
- Tracer Type:
- Neurotransmitter sensor
- Applications:
- Norepinephrine Sensor
Fluorescent probe
- Tracer Type:
- Neurotransmitter sensor
- Applications:
- Norepinephrine Sensor
Fluorescent probe
- Tracer Type:
- Neurotransmitter sensor
- Applications:
- Dopamine Sensor
- Tracer Type:
- Neurotransmitter sensor
- Applications:
- Neurotransmitter Sensor
- Tracer Type:
- Fluorescent labeling
- Tracer Type:
- Fluorescent labeling
- Tracer Type:
- Fluorescent labeling
- Tracer Type:
- Fluorescent labeling
- Tracer Type:
- Recombinase
- iNeuMab™ Anti-ApoC3 BBB Shuttle Antibody (NRZP-1022-ZP3505) (Cat#: NRZP-1022-ZP3505)
- iNeuMab™ Anti-Tau Antibody (NRP-0422-P2293) (Cat#: NRP-0422-P2293)
- iNeuMab™ Anti-TNFα BBB Shuttle Antibody (NRZP-1022-ZP4105) (Cat#: NRZP-1022-ZP4105)
- iNeuMab™ Anti-SEZ6 Antibody (NRP-0422-P517) (Cat#: NRP-0422-P517)
- iNeuMab™ Anti-SEZ6 Antibody (NRP-0422-P515) (Cat#: NRP-0422-P515)
- iNeuMab™ Anti-Amyloid Beta 1-15 Antibody (NRP-0422-P867) (Cat#: NRP-0422-P867)
- iNeuMab™ Anti-Tau Antibody (NRP-0422-P1683) (Cat#: NRP-0422-P1683)
- iNeuMab™ Anti-FGFR1 Antibody (NRP-0422-P1244) (Cat#: NRP-0422-P1244)
- iNeuMab™ Anti-CD20 Antibody (NRP-0422-P1230) (Cat#: NRP-0422-P1230)
- iNeuMab™ Mouse Anti-LRP1 Monoclonal Antibody (CBP3363) (Cat#: NAB-0720-Z6479)
- iNeu™ Human Motor Neurons (Cat#: NCL-2103-P71)
- Immortalized Human Cerebral Microvascular Endothelial Cells (Cat#: NCL-2108-P020)
- Mouse Glioma Cell Line GL-261-Luc (Cat#: NCL-2108P06)
- Green Fluorescent BACE1 Cell Lines (Cat#: NCL2110P214)
- Rat Glioma Cell Line C6 (Cat#: NCL2110P346)
- Green Fluorescent Alpha-synuclein Cell Line (Cat#: NCL2110P209)
- Rat Immortalized Retinal Muller Cell Line rMC-1 (Cat#: NCL-2106-S93)
- Mouse Midbrain Dopaminergic Neuron Cell MN9D (Cat#: NCL2110P059)
- Human Glial (Oligodendrocytic) Hybrid Cell Line (MO3.13) (Cat#: NCL-2108P34)
- Mouse Microglia from C57BL/6 (Cat#: NCL-21P6-082)
- Beta Amyloid (1-40), Aggregation Kit (Cat#: NRZP-0323-ZP199)
- Human Tau Aggregation Kit (Cat#: NRP-0322-P2173)
- Human Poly ADP ribose polymerase,PARP Assay Kit (Cat#: NRZP-1122-ZP62)
- Alpha Synuclein Aggregation Kit (Cat#: NRZP-1122-ZP15)
- Alpha-Synuclein Aggregation Assay Kit (Cat#: NRZP-1122-ZP37)
- Beta Amyloid (1-42), Aggregation Kit (Cat#: NRZP-0323-ZP200)
- Human GFAP ELISA Kit [Colorimetric] (Cat#: NPP2011ZP383)
- Amyloid beta 1-42 Kit (Cat#: NRP-0322-P2170)
- VSV-eGFP (Cat#: NTA-2011-ZP20)
- Dextran, NHS Activated (Cat#: NRZP-0722-ZP124)
- AAV2/9-hEF1a-fDIO-eNpHR 3.0-mCherry-WPRE-pA (Cat#: NTA-2012-ZP78)
- AAV2 Full Capsids, Reference Standards (Cat#: NTC2101070CR)
- Lenti of Mouse synuclein, alpha (Snca) transcript variant (NM_001042451) ORF clone, mGFP Tagged (Cat#: NEP-0521-R0864)
- App Rat amyloid beta (A4) precursor protein (App)(NM_019288) ORF clone, Untagged (Cat#: NEP-0421-R0053)
- Human superoxide dismutase 1, soluble (SOD1) (NM_000454) ORF clone, TurboGFP Tagged (Cat#: NEP-0521-R0748)
- Rat Parkinson disease (autosomal recessive, juvenile) 2, parkin (Park2) (NM_020093) ORF clone/lentiviral particle, Myc-DDK Tagged (Cat#: NEP-0621-R0041)
- Mouse SOD1 shRNA Silencing Adenovirus (Cat#: NV-2106-P14)
- Human huntingtin (HTT) (NM_002111) ORF clone, Myc-DDK Tagged (Cat#: NEP-0521-R0497)
- Human superoxide dismutase 3, extracellular (SOD3) (NM_003102) ORF clone, Untagged (Cat#: NEP-0521-R0808)
- Human apolipoprotein E (APOE) (NM_000041) ORF clone, Untagged (Cat#: NEP-0421-R0232)
- ABCA1 Antisense Oligonucleotide (NV-2106-P27) (Cat#: NV-2106-P27)
- Mouse Parkinson disease (autosomal recessive, early onset) 7 (Park7) (NM_020569) clone, Untagged (Cat#: NEP-0621-R0133)
- NeuroBiologics™ Rat Cerebrospinal Fluid (Cat#: NRZP-0822-ZP496)
- NeuroBiologics™ Monkey Cerebrospinal Fluid (Cat#: NRZP-0822-ZP495)
- NeuroBiologics™ Mouse Cerebrospinal Fluid (Cat#: NRZP-0822-ZP497)
- NeuroBiologics™ Pig Cerebrospinal Fluid (Cat#: NRZP-0822-ZP498)
- NeuroBiologics™ Human Cerebrospinal Fluid (Cat#: NRZP-0822-ZP491)
- NeuroPro™ Anti-Erythropoietin BBB Shuttle Protein (Cat#: NRZP-0423-ZP499)
- NeuroPro™ Anti-ASA BBB Shuttle Protein (Cat#: NRZP-0423-ZP504)
- NeuroPro™ Anti-idursulfase BBB Shuttle Protein (Cat#: NRZP-0423-ZP497)
- NeuroPro™ Anti-EPO BBB Shuttle Protein (Cat#: NRZP-0423-ZP508)
- NeuroPro™ Anti-GDNF BBB Shuttle Protein (Cat#: NRZP-0423-ZP500)
- NeuroPro™ Anti-IDUA BBB Shuttle Protein (Cat#: NRZP-0423-ZP502)
- NeuroPro™ Anti-GDNF BBB Shuttle Protein (Cat#: NRZP-0423-ZP509)
- NeuroPro™ Anti-NAGLU BBB Shuttle Protein (Cat#: NRZP-0423-ZP506)
- NeuroPro™ Anti-IDUA BBB Shuttle Protein (Cat#: NRZP-0423-ZP498)
- NeuroPro™ Anti-SGSH BBB Shuttle Protein (Cat#: NRZP-0423-ZP505)
