- NeuroMab™ Anti-Tau Antibody,Clone NR2218P (Cat#: NRP-0422-P2275)
- NeuroMab™ Mouse Anti-EFNB2 Monoclonal Antibody (CBP1159) (Cat#: NAB-0720-Z4396)
- NeuroMab™ Anti-ApoC3 BBB Shuttle Antibody,Clone NR1738P (Cat#: NRZP-1022-ZP3503)
- NeuroMab™ Anti-SEZ6 Antibody, Clone NR30P (Cat#: NRP-0422-P517)
- NeuroMab™ Anti-Tau Antibody,Clone NR3320P (Cat#: NRP-0422-P1760)
- NeuroMab™ Anti-TREM2 Antibody, Clone NR65P (Cat#: NRP-0422-P792)
- NeuroMab™ Anti-Tau Antibody,Clone NR2944P (Cat#: NRP-0422-P1684)
- NeuroMab™ Anti-Tau Antibody,Clone NR2948P (Cat#: NRP-0422-P1683)
- NeuroMab™ Anti-CD20 Antibody,Clone NR3021P (Cat#: NRP-0422-P1230)
- NeuroMab™ Anti-Alpha Synuclein Antibody,Clone NR3861P (Cat#: NRP-0422-P614)
- Human Blood Brain Barrier Model (Cat#: NCL-2103-P187)
- Human Glioblastoma Cell Line SF126 (Cat#: NCL-2108P35)
- Rat Schwann Cells RSC96, Immortalized (Cat#: NCL-2108P21)
- Mouse Retinal Ganglion Cell Line RGC-5 (Cat#: NCL2110P154)
- Human Glial (Oligodendrocytic) Hybrid Cell Line (MO3.13) (Cat#: NCL-2108P34)
- Human Brain Vascular Pericytes (Cat#: NCL-21P6-015)
- Mouse Microglia from C57BL/6 (Cat#: NCL-21P6-082)
- Human Dental Pulp Stem Cells (Cat#: NRZP-1122-ZP113)
- Human Brain Microvascular Endothelial Cells (Cat#: NCL-2103-P133)
- Human Neurons Isolated from Cortex (Cat#: NCL-21P6-023)
- Human Tau Aggregation Kit (Cat#: NRP-0322-P2173)
- Human Poly ADP ribose polymerase,PARP Assay Kit (Cat#: NRZP-1122-ZP62)
- Alpha Synuclein Aggregation Kit (Cat#: NRZP-1122-ZP15)
- Alpha-Synuclein Aggregation Assay Kit (Cat#: NRZP-1122-ZP37)
- Beta Amyloid (1-40), Aggregation Kit, TTF Assay (Cat#: NRZP-0323-ZP199)
- Human GFAP ELISA Kit [Colorimetric] (Cat#: NPP2011ZP383)
- Amyloid beta 1-42 Kit (Cat#: NRP-0322-P2170)
- Beta Amyloid (1-42), Aggregation Kit (Cat#: NRZP-0323-ZP200)
- pAAV-EF1a-DIO-EGFP-WPRE (Cat#: NTA-2012AD-P285)
- AAV2/9-hEF1a-DIO-mCherry-P2A-TetTox-WPRE-pA (Cat#: NTA-2012-ZP268)
- AAV-mDLX-CRE-tdTomato (Cat#: NRZP-0622-ZP721)
- AAV2/9-hSyn-Flpo-EGFP-WPRE-pA (Cat#: NTA-2012-ZP149)
- AAV2/9-hEF1a-fDIO-eNpHR 3.0-mCherry-WPRE-pA (Cat#: NTA-2012-ZP78)
- AAV2/2Retro-CAG-DIO-EGFP-2A-TetTox-pA [Neural Tracing] (Cat#: NTA-2012-ZP303)
- AAV-EF1a-mCherry-flex-dtA (Cat#: NRZP-0622-ZP616)
- VSV-eGFP (Cat#: NTA-2011-ZP20)
- pAAV-hSyn-DIO-XCaMP-R-WPRE (Cat#: NTA-2012AD-P508)
- pAAV-syn-jGCaMP8m-WPRE (Cat#: NTA-2106-P062)
- Human huntingtin (HTT) (NM_002111) ORF clone, Myc-DDK Tagged (Cat#: NEP-0521-R0497)
- Human apolipoprotein E (APOE) (NM_000041) ORF clone, Untagged (Cat#: NEP-0421-R0232)
- Human superoxide dismutase 3, extracellular (SOD3) (NM_003102) ORF clone, Untagged (Cat#: NEP-0521-R0808)
- Lenti of Mouse synuclein, alpha (Snca) transcript variant (NM_001042451) ORF clone, mGFP Tagged (Cat#: NEP-0521-R0864)
- App Rat amyloid beta (A4) precursor protein (App)(NM_019288) ORF clone, Untagged (Cat#: NEP-0421-R0053)
- Human presenilin 1 (PSEN1), transcript variant 2 (NM_007318) ORF clone, TurboGFP Tagged (Cat#: NEP-0421-R0140)
- Lenti of Human TAR DNA binding protein (TARDBP) (NM_007375) ORF clone, mGFP Tagged (Cat#: NEP-0521-R0832)
- Mouse Parkinson disease (autosomal recessive, early onset) 7 (Park7) (NM_020569) clone, Untagged (Cat#: NEP-0621-R0133)
- Rat Parkinson disease (autosomal recessive, juvenile) 2, parkin (Park2) (NM_020093) ORF clone/lentiviral particle, Myc-DDK Tagged (Cat#: NEP-0621-R0041)
- ABCA1 Antisense Oligonucleotide (AK311445) (Cat#: NV-2106-P27)
- NeuroBiologics™ Pig Cerebrospinal Fluid (Cat#: NRZP-0822-ZP498)
- NeuroBiologics™ Monkey Cerebrospinal Fluid (Cat#: NRZP-0822-ZP495)
- NeuroBiologics™ Rat Cerebrospinal Fluid (Cat#: NRZP-0822-ZP496)
- NeuroBiologics™ Mouse Cerebrospinal Fluid (Cat#: NRZP-0822-ZP497)
- NeuroBiologics™ Human Cerebrospinal Fluid (Cat#: NRZP-0822-ZP491)
- NeuroPro™ Anti-IDS BBB Shuttle Protein, HIRMab-IDS (Cat#: NRZP-0423-ZP503)
- NeuroPro™ Anti-ASA BBB Shuttle Protein, HIRMab-ASA (Cat#: NRZP-0423-ZP504)
- NeuroPro™ Anti-GDNF BBB Shuttle Protein, HIRMab-GDNF (Cat#: NRZP-0423-ZP509)
- NeuroPro™ Anti-TNFR BBB Shuttle Protein, cTfRMAb-TNFR (Cat#: NRZP-0423-ZP501)
- NeuroPro™ Anti-Erythropoietin BBB Shuttle Protein, cTfRMAb-EPO (Cat#: NRZP-0423-ZP499)
- NeuroPro™ Anti-IDUA BBB Shuttle Protein, cTfRMAb-IDUA (Cat#: NRZP-0423-ZP498)
- NeuroPro™ Anti-SGSH BBB Shuttle Protein, HIRMab-SGSH (Cat#: NRZP-0423-ZP505)
- NeuroPro™ Anti-TNFR BBB Shuttle Protein, HIRMab-TNFR (Cat#: NRZP-0423-ZP510)
- NeuroPro™ Anti-IDUA BBB Shuttle Protein, HIRMab-IDUA (Cat#: NRZP-0423-ZP502)
- NeuroPro™ Anti-idursulfase BBB Shuttle Protein, 8D3-IL-1RA (Cat#: NRZP-0423-ZP497)
Viral Tracer Tools
Non-viral conventional tracers are effective tools for visualizing a large number of neural connections. The only specified parameter is the position of the cell body or axon end. They usually come in a form that is easy to inject and can be tested in any target animal because they do not require specific genetically modified strains or genetic methods. However, the use of non-viral conventional tracers is mainly limited to mapping global connections. Most conventional tracers do not have sufficient resolution to reveal connectivity at the level of molecularly defined cell types. They also did not reveal whether axons that terminate in specific locations are in contact with specific cell types or synapses connected to other cells. Conventional tracers can remain outside the cells at the injection site, and they usually mark the injection site or all cell bodies projected at the injection site.
Instead, genetic strategies can be used to target viruses to specific cell types, for example, through specific expression of viral receptors or through expression of recombinase proteins in specific cells to direct productive infection or payload delivery to these cells. In some cases, the virus can be modified to express a small molecule tracer in the target cell type of interest.
Creative Biolabs offers a variety of viral vectors to replace chemical tracers with targeted viral genetics methods.
Table 1: Properties of
Commonly Used Transneuronal/Trans-synaptic Viral Tracers.
Please don’t hesitate to contact us for more details.
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- Tracer Type:
- Neurotransmitter sensor
- Applications:
- cAMP Sensor
AAV-mDLX-CRE-tdTomato [CAT#: NRZP-0622-ZP721]
- Tracer Type:
- Recombinase
- Applications:
- Neural Tracing
AAV-EF1a-mCherry-flex-dtA [CAT#: NRZP-0622-ZP616]
- Tracer Type:
- Fluorescent labeling
- Applications:
- Neural Circuit Mapping
pAAV-EF1a-DIO-EGFP-WPRE [CAT#: NTA-2012AD-P285]
- Tracer Type:
- Fluorescent labeling
- Applications:
- Control
AAV2/9-hSyn-Flpo-EGFP-WPRE-pA [CAT#: NTA-2012-ZP149]
- Tracer Type:
- Recombinase
- Applications:
- Recombinase
rAAV-E-SARE-Cre-ERT2-PEST-WPRE-hGH polyA [CAT#: NTA-2010-TT342]
- Tracer Type:
- Recombinase
- Applications:
- Recombinase
VSV-eGFP [CAT#: NTA-2011-ZP20]
Anterograde, multisynaptic
- Tracer Type:
- Anterograde tracing virus
- Applications:
- Neural Tracing
PRV-CAG-EGFP [CAT#: NTA-2011-ZP14]
Retrograde, multisynaptic
- Tracer Type:
- Retrograde tracing virus
- Applications:
- Neural Tracing
- Tracer Type:
- Tetracycline System
- Applications:
- Neural Tracing
- Tracer Type:
- Fluorescent labeling
- Applications:
- Multi-signature neuronal labeling; IBIST
- Tracer Type:
- Fluorescent labeling
- Applications:
- Multi-signature neuronal labeling; IBIST
- Tracer Type:
- Fluorescent labeling
- Applications:
- Multi-signature neuronal labeling; IBIST
- Tracer Type:
- Fluorescent labeling
- Applications:
- Multi-signature neuronal labeling; IBIST
- Tracer Type:
- Fluorescent labeling
- Applications:
- Multi-signature neuronal labeling; IBIST
- Tracer Type:
- Fluorescent labeling
- Applications:
- Multi-signature neuronal labeling; IBIST
- Tracer Type:
- Fluorescent labeling
- Applications:
- Multi-signature neuronal labeling; IBIST
Custom Vector Development Service
- Tracer Type:
- Neurotransmitter sensor
- Applications:
- cAMP Indicator
Custom Vector Development Service
- Tracer Type:
- Fluorescent labeling
Custom Vector Development Service
- Tracer Type:
- Fluorescent labeling
Custom Vector Development Service
- Tracer Type:
- Neurotransmitter sensor
Fluorescent probe
GRAB peptide sensors for detecting corticotropin-releasing factor.
- Tracer Type:
- Neurotransmitter sensor
- Applications:
- CRH Sensor
- Tracer Type:
- Neurotransmitter sensor
- Applications:
- Neurotransmitter Sensor
Fluorescent probe
GRAB peptide sensors for detecting somatostatin.
- Tracer Type:
- Neurotransmitter sensor
- Applications:
- Somatostatin Sensor
- Tracer Type:
- Neurotransmitter sensor
- Applications:
- Endocannabinoid Sensor
- Tracer Type:
- Neurotransmitter sensor
- Applications:
- Neurotransmitter Sensor
- Tracer Type:
- Neurotransmitter sensor
- Applications:
- ATP Sensor
- Tracer Type:
- Neurotransmitter Sensor
- Applications:
- Orexin Sensor
- Tracer Type:
- Neurotransmitter Sensor
- Applications:
- Orexin Sensor
- Tracer Type:
- Neurotransmitter Sensor
- Applications:
- Orexin Sensor
- Tracer Type:
- Neurotransmitter Sensor
- Applications:
- Orexin Sensor
