Neuromodulation has developed rapidly in recent years, and it involves a wide range of implantable and non-invasive technology-based approaches for the treatment of neurological and neuropsychiatric disorders. Neuromodulation is the physiological process in where a series of neuromodulators are used to regulate diverse functions and activities of neurons. Neuromodulators typically bind to metabotropic and GPCRs to initiate a second messenger signaling cascade that induces a broad, long-lasting signal. The effects of neuromodulators include altering the internal discharge activity, increasing or decreasing voltage-dependent currents, altering synaptic efficacy, increasing synaptic activity and reconfiguration of synaptic connectivity.
Besides, oral medication and ablative neurosurgical procedures can obtain similar therapeutic outcomes. However, neuromodulation has higher spatiotemporal precision than oral medication combined with reversibility that is absent in ablative procedures. Till now, neuromodulation has been used to treat a number of diseases, such as obsessive compulsive disorder, bladder control, epilepsy, spasticity, depression, movement disorders, sensory disabilities, chronic pain, spinal cord injury and so on.
As a pioneer of the neuroscience research field, Creative Biolabs has developed and produced a series of neuromodulators including agonists and inhibitors to assist neuroscience research.
What We Provide
We also provide customized product development according to your specific needs. Please don’t hesitate to contact us for more details.