Product
IonON™ Human CFTR Recombinant Stable Cell Line
[CAT#: NCL-7P069]
Creative Biolabs provides numerous IonON cell models of ion channels to meet your drug discovery needs.
- Species:
- Human
- Applications:
- GPCR Screening
- Cell Types:
- GPCR Cell
Certificate of Analysis Lookup
To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number
To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number
Product Overview
Description
The excitability of neurons, skeletal muscle, cardiac muscle, and smooth muscle, as well as the regulation of cell volume, transepithelial salt transport, and acidification of intracellular and extracellular compartments, are all regulated by chloride ion channels, a series of anion selective channels. The CFTR gene produces the membrane protein and chloride channel known as the cystic fibrosis transmembrane conductance regulator (CFTR) in vertebrates. The pancreas, intestinal tissues, sweat glands, and respiratory system all express CFTR ion channels. These tissues' surface expression or diminished function of mutant channels is congruent with the signs and symptoms of the illness.
Cell Types
GPCR Cell
Applications
GPCR Screening
Application Notes
Electrophysiology assay (Conventional and automated patch clamp platforms)
Species
Human
Properties
Size
2 Vials of mycoplasma-free cells, 1 mL per vial aliquots containing 2M to 4M cells/mL in DMSO
Mycoplasma Testing
The cell line has been screened using the Mycoplasma Detection Kit to confirm the absence of Mycoplasma contamination.
Shipping
Dry ice.
Storage
Liquid Nitrogen
Research Use Only
For research use only
Quality Control
All cells test negative for mycoplasma, bacteria, yeast, and fungi.
Target Details
Target
CFTR
Official Name
CFTR
Full Name
CFTR
Publications
Publications (0)
Neural Cell Lines
For Research Use Only. Not For Clinical Use.
