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Creative Biolabs
Product

IonON™ Human GABAA α4/β3/γ2 Recombinant Stable Cell Line

[CAT#: NCL-7P072]

Creative Biolabs provides numerous IonON cell models of ion channels to meet your drug discovery needs.

Species:
Human
Applications:
GPCR Screening
Cell Types:
GPCR Cell

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Certificate of Analysis Lookup
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Product Overview

Description

The primary inhibitory neurotransmitter in the CNS is gamma-aminobutyric acid (GABA)-gated ion channels. Five protein subunits, typically,, and or, make up a typical GABA ion channel's pentameric shape, which comes together to form a central ion-conducting hole through the cell membrane. Because different combinations produce distinct effects, the precise subunit composition is particularly crucial.

Cell Types

GPCR Cell

Applications

GPCR Screening

Application Notes

Electrophysiology assay (Conventional and automated patch clamp platforms)

Species

Human
Properties

Size

2 Vials of mycoplasma-free cells, 1 mL per vial aliquots containing 2M to 4M cells/mL in DMSO

Mycoplasma Testing

The cell line has been screened using the Mycoplasma Detection Kit to confirm the absence of Mycoplasma contamination.

Shipping

Dry ice.

Storage

Liquid Nitrogen

Research Use Only

For research use only

Quality Control

All cells test negative for mycoplasma, bacteria, yeast, and fungi.
Target Details

Target

GABAA α4/β3/γ2

Official Name

; GABAA α4/β3/γ2;

Full Name

GABAA α4/β3/γ2
Publications

Publications (0)

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For Research Use Only. Not For Clinical Use.
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