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Creative Biolabs
Product

IonON™ Human Nav1.5 Recombinant Stable Cell Line

[CAT#: NCL-7P115]

Creative Biolabs provides numerous IonON cell models of ion channels to meet your drug discovery needs.

Species:
Human
Applications:
GPCR Screening
Cell Types:
GPCR Cell

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Product Overview

Description

Action potential initiation and conduction are both facilitated by the presence of hNav1.5, which is expressed in cardiomyocytes. QT prolongation and ventricular fibrillation are brought on by Nav1.5 mutations. Local anaesthetics and antiarrhythmic medications both have adverse effects that are directed at the ion channel.

Cell Types

GPCR Cell

Applications

GPCR Screening

Application Notes

Electrophysiology assay (Conventional and automated patch clamp platforms)

Species

Human
Properties

Size

2 Vials of mycoplasma-free cells, 1 mL per vial aliquots containing 2M to 4M cells/mL in DMSO

Mycoplasma Testing

The cell line has been screened using the Mycoplasma Detection Kit to confirm the absence of Mycoplasma contamination.

Shipping

Dry ice.

Storage

Liquid Nitrogen

Research Use Only

For research use only

Quality Control

All cells test negative for mycoplasma, bacteria, yeast, and fungi.
Target Details

Target

Nav1.5

Official Name

SCN5A

Full Name

Nav1.5

Alternative Names

SCN5A; CDCD2; CMD1E; CMPD2; HB1; HB2; HBBD; HH1; ICCD; IVF; LQT3; Nav1.5; PFHB1; SSS1; VF1; sodium voltage-gated channel alpha subunit 5
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For Research Use Only. Not For Clinical Use.
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