Product
IonON™ Human Nav1.6 Recombinant Stable Cell Line
[CAT#: NCL-7P116]
Creative Biolabs provides numerous IonON cell models of ion channels to meet your drug discovery needs.
- Species:
- Human
- Applications:
- GPCR Screening
- Cell Types:
- GPCR Cell
Certificate of Analysis Lookup
To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number
To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number
Product Overview
Description
The Ranvier nodes of the sensory and motor axons of the PNS, as well as the output neurons of the cerebellum, cortex, and hippocampus of the central nervous system, are the major sites of hNav1.6 expression. Action potentials in central neurons and their myelinated axons are initiated and transmitted by hNav1.6. Mice with motor endplate disease and cerebellar ataxia are caused by mutations in the Nav1.6 gene or its deletion. Potential targets for analgesic and anti-epileptic medications include this channel.
Cell Types
GPCR Cell
Applications
GPCR Screening
Application Notes
Electrophysiology assay (Conventional and automated patch clamp platforms)
Species
Human
Properties
Size
2 Vials of mycoplasma-free cells, 1 mL per vial aliquots containing 2M to 4M cells/mL in DMSO
Mycoplasma Testing
The cell line has been screened using the Mycoplasma Detection Kit to confirm the absence of Mycoplasma contamination.
Shipping
Dry ice.
Storage
Liquid Nitrogen
Research Use Only
For research use only
Quality Control
All cells test negative for mycoplasma, bacteria, yeast, and fungi.
Target Details
Target
Nav1.6
Official Name
SCN8A
Full Name
Nav1.6
Alternative Names
SCN8A; CERIII; CIAT; EIEE13; MED; NaCh6; Nav1.6; PN4; sodium voltage-gated channel alpha subunit 8; BFIS5; MYOCL2
Publications
Publications (0)
Neural Cell Lines
For Research Use Only. Not For Clinical Use.
