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Creative Biolabs
Product

IonON™ Human TRPV4 Recombinant Stable Cell Line

[CAT#: NCL-7P123]

Creative Biolabs provides numerous IonON cell models of ion channels to meet your drug discovery needs.

Species:
Human
Applications:
GPCR Screening
Cell Types:
GPCR Cell

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Product Overview

Description

The calcium channel-functioning proteins are made according to instructions from the TRPV4 gene. This channel, which is present in many different types of cells and tissues, delivers positively charged calcium atoms (calcium ions) to the cell membrane. TRPV4 channels are known to be involved in a wide range of bodily processes. These include the formation of the tough yet flexible tissues that make up the majority of the bones throughout early development, such as bones and cartilage. Additionally, it plays a role in maintaining the body's water balance (osmotic adjustment) and some feelings, particularly unpleasant ones.

Cell Types

GPCR Cell

Applications

GPCR Screening

Application Notes

Electrophysiology assay (Conventional and automated patch clamp platforms)

Species

Human
Properties

Size

2 Vials of mycoplasma-free cells, 1 mL per vial aliquots containing 2M to 4M cells/mL in DMSO

Mycoplasma Testing

The cell line has been screened using the Mycoplasma Detection Kit to confirm the absence of Mycoplasma contamination.

Shipping

Dry ice.

Storage

Liquid Nitrogen

Research Use Only

For research use only

Quality Control

All cells test negative for mycoplasma, bacteria, yeast, and fungi.
Target Details

Target

TRPV4

Official Name

TRPV4

Alternative Names

Transient Receptor Potential Cation Channel Subfamily V Member 4; Osmosensitive Transient Receptor Potential Channel 4; Transient Receptor Potential Protein 12; Vanilloid Receptor-Like Channel 2; Osm-9-Like TRP Channel 4; OTRPC4; TRP12; VROAC; VRL2; Transient Receptor Potential Cation Channel; Subfamily V; Member 4; Vanilloid Receptor-Related Osmotically Activated Channel; Vanilloid Receptor-Related Osmotically-Activated Channel;
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For Research Use Only. Not For Clinical Use.
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