Product

Mouse mCCR3 β-Arrestin GPCR Cell Line [CHO-K1]

[CAT#: NCL-7P849]

Species:: Mouse

Applications:: GPCR Screening

Cell Types:: GPCR Cell

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Product Overview

Description

The β-Arrestin GPCR cell line NCL-7P849 at Creative Biolabs is engineered to co-express PK-labeled GPCR and enzyme receptor (EA) labeled β-Arrestin. Activation of GPCR-PK induces the recruitment of β-Arrestin-EA, forcing the two enzyme fragments to complement each other.

Features

Coupling: Gi/Go
β-Arrestin isoform: β-Arrestin-2
Tag: PK1
Agonist/Ligand: Recombinant Murine Eotaxin-2 (CCL24)

Cell Types

GPCR Cell

Cell Location

β-Arrestin

Applications

GPCR Screening

Assay

GPCR Screening Assay

Readout

β-Arrestin

Assay Characteristics

Coupling: Gi/Go
β-Arrestin isoform: β-Arrestin-2
Tag: PK1
Agonist/Ligand: Recombinant Murine Eotaxin-2 (CCL24)

Species

Mouse

Properties

Shipping

Dry ice.

Storage

Liquid Nitrogen

Research Use Only

For research use only

Quality Control

All cells test negative for mycoplasma, bacteria, yeast, and fungi.

Target Details

Target

mCCR3

Official Name

CCR3

Alternative Names

C-C CKR-3; CC chemokine receptor 3; CC-CKR-3; CC-CKR3; CCR-3; CKR3; Cmkbr1l2; Cmkbr3; MIP-1 alpha RL2; MIP-1 alphaRL2; chemokine (C-C motif) receptor 3; chemokine (C-C) receptor 1;-like 2; chemokine (C-C) receptor 3; macrophage inflammatory protein 1-alpha receptor-like 2; probable C-C chemokine receptor type 3

Publications