Product
NeuroMab™ Anti-Amyloid Beta 1-15 Antibody, Clone mAb158
[CAT#: NRP-0422-P2292]
- Host Species:
- Mouse; Humanzied
- Species Reactivity:
- Human
- Applications:
- Inhib; In Vitro; In Vivo
Certificate of Analysis Lookup
To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number
To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number
SPECIFIC INQUIRY
inquiryProduct Overview
Description
The mouse monoclonal antibody mAb158 selectively binds to large, soluble Aβ protofibrils. Subsequent studies in mouse neuron-glial co-cultures showed that mAb158 may protect neurons, i.e., reduce Aβ protofibril toxicity, by counteracting the pathological accumulation of these protofibrils in astrocytes.
Species Reactivity
Human
Clonality
Monoclonal
Host Species
Mouse; Humanzied
Isotype
IgG
Clone Number
mAb158 (Lecanemab, BAN2401)
Applications
Inhib; In Vitro; In Vivo
Relevant Diseases
Alzheimer's Disease
Product Properties
Formulation
PBS only
Preservatives
BSA Free
Concentration
1mg/mL
Purification
Purified recombinant IgG prepared by affinity chromatography on Protein A from a mammalian cell line
Purity
>95% by SDS PAGE or HPLC
Endotoxin Level
Regular Endotoxin < 5 EU/mg
Low Endotoxin < 1 EU/mg
Low Endotoxin < 1 EU/mg
Shipping
Gel Packs
Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Research Use Only
For research use only
Target
Target
Amyloid Beta 1-15
Official Name
Amyloid Beta
Alternative Names
APP; Aβ; Abeta; Amyloid β
Publications
Publications (0)
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For Research Use Only. Not For Clinical Use.
