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Creative Biolabs
Product

HOT NeuroMab™ Anti-Amyloid Beta 1-15 Antibody,Clone NR3281P

[CAT#: NRP-0422-P2292] Review(5) Q&As(3)

Host Species:
Mouse; Humanzied
Species Reactivity:
Human
Applications:
Inhib; In Vitro; In Vivo

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Product Overview

Description

The mouse monoclonal antibody mAb158 selectively binds to large, soluble Aβ protofibrils. Subsequent studies in mouse neuron-glial co-cultures showed that mAb158 may protect neurons, i.e., reduce Aβ protofibril toxicity, by counteracting the pathological accumulation of these protofibrils in astrocytes.

Species Reactivity

Human

Clonality

Monoclonal

Host Species

Mouse; Humanzied

Isotype

IgG

Clone Number

NR3281P

Applications

Inhib; In Vitro; In Vivo

Relevant Diseases

Alzheimer's Disease
Product Properties

Formulation

PBS only

Preservatives

BSA Free

Concentration

1mg/mL

Purification

Purified recombinant IgG prepared by affinity chromatography on Protein A from a mammalian cell line

Purity

>95% by SDS PAGE or HPLC

Endotoxin Level

Regular Endotoxin < 5 EU/mg
Low Endotoxin < 1 EU/mg

Shipping

Gel Packs

Storage

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Research Use Only

For research use only
Target

Target

AmyloidBeta1-15

Official Name

Amyloid Beta

Full Name

Amyloid Beta

Alternative Names

APP; Aβ; Abeta; Amyloid β
Publications

Publications (0)

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Customer Reviews and Q&As
Customer Reviews Average Customer Ratings Overall
5.0
user
Excellent
Provided consistently reliable results
As ainvestigator focusing on amyloid pathologies, I've found mAb158 to be invaluable. The antibody's high affinity for its target has allowed us to detect amyloid deposits with great accuracy. It has definitely elevated the quality of our western blot analyses.
user
Excellent
It has streamlined our workflow and provided clear, distinct signals
We've used several antibodies in our lab, but mAb158 stands out due to its exceptional sensitivity and specificity. It has facilitated our ELISA assays, making them more robust and reproducible. An essential tool for any lab studying amyloid beta.
user
Excellent
I highly recommend it for its precision and robustness
Our lab has benefited immensely from using mAb158. The antibody's reliability and precision in detecting amyloid beta in various assays have made it a favorite among our team. It’s particularly effective in immunohistochemistry applications.
user
Excellent
We’ve used mAb158 extensively in our studies
mAb158 has provided us with high-quality results in our immunohistochemistry studies. The antibody's ability to bind selectively to amyloid beta 1-15 has enhanced the clarity of our staining, making it easier to identify and quantify amyloid deposits.
user
Excellent
An essential tool for amyloid beta studies
This antibody has been an exceptional antibody for our research. Its ability to consistently produce high-quality results in immunohistochemistry has been invaluable. The clarity and specificity of the staining have been particularly noteworthy.
Q&As
Can the antibody be used in combination with other research reagents or antibodies?
The antibody can be used in combination with other research reagents or antibodies to enhance the study of amyloid beta pathology and potential therapeutic interventions. Our team can provide guidance on compatible combinations and optimal experimental design for your specific research needs.
Can the antibody be customized or modified for specific research requirements?
The antibody can be customized or modified to meet specific research requirements or experimental conditions. Our team of experts can work with you to develop personalized solutions tailored to your research needs, ensuring the antibody's compatibility and effectiveness in your project.
Is there any data available on the performance of this antibody in research studies?
Yes, we have data available on the specificity and performance of anti-Amyloid Beta 1-15 antibody, clone mAb158 in research studies. Please contact us for more information.
For Research Use Only. Not For Clinical Use.
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