Creative Biolabs

NeuroMab™ Anti-Kv3.3 potassium channel, Clone N375/67

[CAT#: NRP-0422-P222]

Species Reactivity:
Rat; Mouse; Human
Applications:
WB; IHC; ICC

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Immunogen
Fusion protein amino acids 628-728 (cytoplasmic C-terminus) of mouse Kv3.3b (also known as Potassium voltage-gated channel subfamily C member 3, KSHIIID and Kcnc3, accession number Q63959)
Human: 96% identity (94/97 amino acids identical)
Rat: 90% identity (96/106 amino acids identical)
100% identity with Kv3.3a for first 30 amino acids (AGGLGIMGLPPLPAPGEPCPLEEVIETNRA)
<40% identity with Kv3.4 or Kv3.2
Species Reactivity
Rat; Mouse; Human
Clonality
Monoclonal
Isotype
IgG1
Clone Number
N375/67
Applications
WB; IHC; ICC
Application Notes
Cross-reacts with Kv3.3a;Does not cross-react with Kv3.4 or Kv3.2
Research Areas
K+ channels
Conjugation
Unconjugated
Research Use Only
For reseaech use only, not for human or dignostic use.
Target
KCNC3
Official Name
KCNC3
Full Name
Kv3.3 K+ channel
Alternative Names
Potassium Voltage-Gated Channel Subfamily C Member 3; Potassium Channel; Voltage Gated Shaw Related Subfamily C; Member 3; Potassium Voltage-Gated Channel; Shaw-Related Subfamily; Member 3; Voltage-Gated Potassium Channel Subunit Kv3.3; KSHIIID; Shaw-Related Voltage-Gated Potassium Channel Protein 3;
Uniprot ID
Q63959
IB

Fig. 1 Immunoblot against adult rat brain membrane (RBM) fractions and extracts of COS cells transiently transfected with untagged Kv3.3a, Kv3.3b or Kv2.1 plasmid probed with N375/67 (left) or N52A/42 (right) TC supe.

IHC

Fig. 2 Adult rat hippocampus immunohistochemistry.

IHC

Fig. 3 Adult rat whole brain immunohistochemistry.

IB

Fig. 4 Adult rat brain membrane immunoblot.

For Research Use Only. Not For Clinical Use.
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