NeuroMab™ Anti-Kv3.3 potassium channel, Clone N375/67 (CBP8323)

Product Overview

Immunogen

Fusion protein amino acids 628-728 (cytoplasmic C-terminus) of mouse Kv3.3b (also known as Potassium voltage-gated channel subfamily C member 3, KSHIIID and Kcnc3, accession number Q63959)
Human: 96% identity (94/97 amino acids identical)
Rat: 90% identity (96/106 amino acids identical)
100% identity with Kv3.3a for first 30 amino acids (AGGLGIMGLPPLPAPGEPCPLEEVIETNRA)
<40% identity with Kv3.4 or Kv3.2

Species Reactivity

Rat; Mouse; Human

Clonality

Monoclonal

Isotype

IgG1

Clone Number

CBP8323

Applications

WB; IHC; ICC

Application Notes

Cross-reacts with Kv3.3a;Does not cross-react with Kv3.4 or Kv3.2

Research Areas

K+ channels

Conjugation

Unconjugated

Product Properties

Research Use Only

For reseaech use only, not for human or dignostic use.

Target

KCNC3

Official Name

KCNC3

Full Name

Kv3.3 K+ channel

Alternative Names

Potassium Voltage-Gated Channel Subfamily C Member 3; Potassium Channel; Voltage Gated Shaw Related Subfamily C; Member 3; Potassium Voltage-Gated Channel; Shaw-Related Subfamily; Member 3; Voltage-Gated Potassium Channel Subunit Kv3.3; KSHIIID; Shaw-Related Voltage-Gated Potassium Channel Protein 3;

Uniprot ID

Q63959

Product Pictures

Fig. 1 Immunoblot against adult rat brain membrane (RBM) fractions and extracts of COS cells transiently transfected with untagged Kv3.3a, Kv3.3b or Kv2.1 plasmid probed with N375/67 (left) or N52A/42 (right) TC supe.