NeuroMab™ Anti-MMP9 BBB Shuttle Antibody, Clone AB0046
- Host Species:
- Mouse; Chimeric
- Species Reactivity:
- Human
- Applications:
- ELISA; IHC; In Vitro; In Vivo
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Notes: The BBB antibody is made-to order and available in a customized format. Please don't hesitate contact us for more details.
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Figure 1 shows immunohistochemistry (IHC) performed on serial sections of frozen colon from vehicle-treated mice (A) and AB0046-treated mice (B).
Figure 2 is a graph showing the results of endoscopic evaluations performed on all animal groups on days 10 and 14 (end date).
The figure shows the average endoscopy score (+/− SEM) from day 6 to day 14 and the arrow indicates the day of AB0046 administration (or other treatment).
Figure 3 shows representative Figures of MMP9 IHC of colon FFPE sections from the study
Figure 4 is a graph showing the results of clinical scores and lower extremity scores.
This is a graph showing the clinical and lower limb scores resulting from the study described in Example 7. The efficacy of mouse surrogate anti-MMP9 antibody (AB0046) and anti-human MMP9 antibody (AB0041) in the mouse CIA model of rheumatoid arthritis and the rat CIA model has been shown. MTX = methotrexate; Non Dis. = Non-disease.
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