NeuroMab™ Anti-PCSK9 BBB Shuttle Antibody, Clone 15.14.2
- Host Species:
- Human
- Species Reactivity:
- Human
- Applications:
- ELISA; Block; Inhib; In Vitro; In Vivo
To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
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Notes: The BBB antibody is made-to order and available in a customized format. Please don't hesitate contact us for more details.
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Figure 1 is an ELISA experiment of human antibody binding to human PCSK9.
Figure 2 represents the comparison of antibody 18.156.8 and reference antibodies 24B9.1, 12H11.1 and BMK.115 with respect to binding to human PCSK9 as determined by the ELISA method.
Figure 3 shows the comparison results of antibody 18.156.8 and reference antibody 24B9.1, 12H11.1 and BMK.115 blocking PCSK9 and LDLR binding as determined by ELISA method.
Figure 4 shows the ability of antibody 18.156.8 and reference antibodies 12H11.1 and BMK.115 to restore LDL uptake in HepG2 cells.
Figure 5 shows the experimental results of anti-PCSK9 antibodies 15.14.2-uAb1-IgG4L, fully human 17.72.3-uAb1-IgG4K and 19.3.8-uAb1-IgG4L in restoring LDL uptake in hepatocellular carcinoma (HepG2) cells.
Figure 6 shows human antibody blocking PCSK9 to be tested using the LDL-R panel ELISA.
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