Product
NeuroMab™ Mouse Anti-Human TPP1 Monoclonal Antibody (CBP2489)
[CAT#: NAB2010611LS]
Anti TPP1 Monoclonal Antibody [HRP]
- Host Species:
- Mouse
- Species Reactivity:
- Human
- Applications:
- WB; IHC-P
Certificate of Analysis Lookup
To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number
To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number
SPECIFIC INQUIRY
inquiryProduct Overview
Description
TPP1 is a member of the sedolisin family of serine proteases. The proenzyme is activated in the lysosome by auto-proteolysis where it cleaves tripeptides from the N-termini of substrates. Mutations of TPP1 are associated with late-infantile neuronal ceroid lipofuscinosis and Spinocerebellar Ataxia, Autosomal Recessive 7.
Immunogen
Recombinant mature human TPP1 expressed in E. coli.
Species Reactivity
Human
Clonality
Monoclonal
Host Species
Mouse
Isotype
IgG2b, κ
Clone Number
CBP2489
Applications
WB; IHC-P
Application Notes
WB (1.0-5.0 µg/mL); IHC-P (1.0-5.0 µg/mL)
Relevant Diseases
Brain Tumors; Alzheimer's Disease; Parkinson's Disease; Neurocutaneous Syndromes
Research Areas
Neuroinflammation
Conjugation
Unconjugated; APC; PE; HRP; Biotin; FITC; Alexa Fluor 488; Alexa Fluor 700; Alexa Fluor 647; Alexa Fluor 750; Alexa Fluor 594; Alexa Fluor 350; Alexa Fluor 1821
Product Properties
Form
Liquid
Formulation
This antibody is provided in 50% glycerol in aqueous buffered solutions with preservatives.PreparationThe antibody was purified by affinity chromatography and conjugat
Concentration
0.5 mg/mL
Purification
Affinity chromatography
Purity
>95%, as determined by Coomassie stained SDS-PAGE.
Endotoxin Level
Low Endotoxin
Shipping
The product is shipped at 4°C. Upon receipt, store it immediately at the recommended temperature.
Storage
Upon receipt, the antibody solution should be stored undiluted at -20°C, and protected from prolonged exposure to light.
Handling Advice
Upon receipt, the antibody solution should be stored undiluted at -20°C, and protected from prolonged exposure to light.
Research Use Only
For research use only, not for diagnostic or therapeutic use.
Target
Target
TPP1
Official Name
TPP1
Full Name
Tripeptidyl Peptidase 1
Alternative Names
Tripeptidyl Peptidase 1; Cell Growth-Inhibiting Gene 1 Protein; Tripeptidyl Aminopeptidase; Tripeptidyl Peptidase I; EC 3.4.14.9; TPP-1; CLN2; LPIC; Ceroid-Lipofuscinosis; Neuronal 2; Late Infantile (Jansky-Bielschowsky Disease); Spinocerebellar Ataxia; Autosomal Recessive 7;
References
1. Getty AL, Pearce DA. 2011. Cell Mol. Life Sci. 68:453-74.
2. Cárcel-Trullols J, et al. 2015. Biochim. Biophys. Acta. 2242-55.
3. Kyttälä A, et al. 2006. Biochim Biophys Acta. 920-33.
2. Cárcel-Trullols J, et al. 2015. Biochim. Biophys. Acta. 2242-55.
3. Kyttälä A, et al. 2006. Biochim Biophys Acta. 920-33.
Publications
Publications (0)
Neural Antibodies
Neural Cell Lines
For Research Use Only. Not For Clinical Use.
