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Creative Biolabs
Product

NeuroMab™ Anti-Shank1 and Shank3, Clone N367/51 (CBP8486)

[CAT#: NRP-0422-P385]

Species Reactivity:
Rat; Mouse
Applications:
WB; IHC; ICC

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Product Overview

Immunogen

Fusion protein amino acids 538-626 (SH3 domain) of rat Shank3 (also known as SH3 and multiple ankyrin repeat domains protein 3, Proline-rich synapse-associated protein 2, ProSAP2, PSAP2, SPANK-2 and Kiaa1650, accession number Q9JLU4)
Mouse: 100% identity (89/89 amino acids identical)
Human: 97% identity (87/89 amino acids identical)
~70% identity with Shank1 and Shank2

Species Reactivity

Rat; Mouse

Clonality

Monoclonal

Isotype

IgG2a

Clone Number

CBP8486

Applications

WB; IHC; ICC

Application Notes

Cross-reacts with Shank1;Does not cross-react with Shank2

Research Areas

Scaffolds

Conjugation

Unconjugated
Product Properties

Research Use Only

For reseaech use only, not for human or dignostic use.
Target

Target

SHANK1SHANK3

Official Name

Shank1/Shank3

Full Name

Shank1 and Shank3

Alternative Names

Shank postsynaptic density protein Antibody, SH3 and multiple ankyrin repeat domains 3 Antibody, Proline rich synapse associated protein 2 Antibody, Proline-rich synapse-associated protein 2 Antibody, ProSAP2 Antibody, PSAP2 Antibody, Antibody, SH3 and multiple ankyrin repeat domains protein 3 Antibody, SH3/ankyrin domain gene 3,Shank3b Antibody, SPANK 2 Antibody, SPANK2 Antibody, KAP/SAPAP interacting protein Antibody, OTTHUMP00000174437 Antibody, SH3 and multiple ankyrin repeat domains 1 Antibody, SH3 and multiple ankyrin repeat domains protein 1 Antibody, SH3/ankyrin domain gene 1 Antibody, SHANK 1 Antibody, Shank1 Antibody, Shank1a Antibody, Somatostatin receptor interacting protein Antibody, Somatostatin receptor-interacting protein Antibody, SPANK 1 Antibody, SPANK1 Antibody, SSTR interacting protein Antibody, SSTR-interacting protein Antibody, SSTRIP Antibody, Synamon Antibody, AI841104 Antibody, DEL22q13.3 Antibody, KIAA1650 Antibody; SH3 And Multiple Ankyrin Repeat Domains 1; Somatostatin Receptor-Interacting Protein; SSTR-Interacting Protein; SSTRIP; SH3 And Multiple Ankyrin Repeat Domains Protein 1; SPANK-1; Synamon; Shank1
Product Pictures
IB

Fig. 1 Adult rat brain membrane (RBM) and transfected cell immunoblot: extracts of RBM and COS cells transiently transfected with HA-tagged Shank1, Shank2, Shank3 or untagged Kv2.1 plasmid and probed with N367/51 (left) or N23B/49 (right) TC supe.

IHC

Fig. 2 Adult rat hippocampus immunohistochemistry.

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