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Creative Biolabs
Product

NeuroMab™ Anti-SUR1, Clone N289/16 (CBP8500)

[CAT#: NRP-0422-P399]

Species Reactivity:
Mouse; Rat
Applications:
WB; IHC; ICC

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Product Overview

Immunogen

Fusion protein amino acids 1548-1582 (LVMVLKRGAILEFDKPEKLLSQKDSVFASFVRADK, cytoplasmic C-terminus) of rat SUR1 (also known as Sulfonylurea receptor 1, SUR, HRINS, ATP binding cassette transporter subfamily C member 8 and Abcc8, accession number Q09429) Mouse: 100% identity (35/35 amino acids identical)
Human: 94% identity (33/35 amino acids identical)
Similar % identity with other isoforms
>70% identity with SUR2B

Species Reactivity

Mouse; Rat

Clonality

Monoclonal

Isotype

IgG1

Clone Number

CBP8500

Applications

WB; IHC; ICC

Application Notes

Does not cross-react with SUR2B

Conjugation

Unconjugated
Product Properties

Research Use Only

For reseaech use only, not for human or dignostic use.
Target

Target

Abcc8

Official Name

ABCC8

Full Name

SUR1

Alternative Names

AM60008PU-N Antibody, ABC36 Antibody, Abcc8 Antibody, ATP binding cassette sub family C member 8 Antibody, HHF1 Antibody, HRINS Antibody, MRP8 Antibody, PHHI Antibody, SUR Antibody, SUR1 Antibody, Sulfonylurea receptor (hyperinsulinemia) Antibody, ATP binding cassette sub family C (CFTR/MRP) member 8 Antibody, ATP binding cassette transporter sub family C member 8 (1) Antibody, ATP-binding cassette sub-family C member 8 Antibody, HI Antibody, PHHI Antibody, Sulfonylurea receptor 1 Antibody, SUR1delta2 Antibody, TNDM2 Antibody; ATP Binding Cassette Subfamily C Member 8; ATP-Binding Cassette, Sub-Family C (CFTR/MRP), Member 8; Sulfonylurea Receptor (Hyperinsulinemia); Sulfonylurea Receptor 1; HRINS; SUR1; SUR; ATP-Binding Cassette Transporter Sub-Family C Member 8; ATP-Binding Cassette Sub-Family C Member 8

Uniprot ID

Q09429
Product Pictures
IB

Fig. 1 Immunoblot versus crude brain membrane preparations from rat (RBM), SUR1 wild-type (WT) and knockout (KO) mice and probed with N289/16 (left), N52A/42 (center) and K89/34 (right) TC supe.

IHC

Fig. 2 Adult rat hippocampus immunohistochemistry (with antigen retrieval via Na citrate pretreatment).

IF

Fig. 3 Immunofluorescence against SUR1 WT (left) and null mutant (right) mouse striatum and stained with N289/16 (green) and commercial antibody against Tyrosine Hydroxylase (blue).

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