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Creative Biolabs
Product

NeuroMab™ Anti-GluN2B Antibody, Clone Fab2

[CAT#: NRZP-1222-ZP806]

Host Species:
Mouse
Species Reactivity:
Human
Applications:
Block; Inhib; In Vitro

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Product Overview

Description

N-methyl-D-aspartate receptors (NMDARs) are critically involved in basic brain functions and neurodegeneration as well as tumor invasiveness. Targeting specific subtypes of NMDARs with distinct activities has been considered an effective therapeutic strategy for neurological disorders and diseases. This inhibitory antibody recognizes the amino terminal domain of the GluN2B subunit and increases the population of the non-active conformational state.

Species Reactivity

Human

Host Species

Mouse

Clone Number

Fab2

Applications

Block; Inhib; In Vitro
Target

Target

GRIN2B

Official Name

GRIN2B

Full Name

Glutamate [NMDA] receptor subunit epsilon-2

Alternative Names

GRIN2B; GluN2B; MRD6; NMDAR2B; NR2B; hNR3; EIEE27; glutamate ionotropic receptor NMDA type subunit 2B; NR3
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