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Creative Biolabs
Product

NeuroMab™ Anti-Integrin αvβ8 BBB Shuttle Antibody, Clone 11D12v2

[CAT#: NRZP-1222-ZP1217]

Host Species:
Mouse
Species Reactivity:
Human
Applications:
Inhib; Block; In Vitro

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Product Overview

Description

Integrin αvβ8 binds with exquisite specificity to latent transforming growth factor-β (L-TGF-β). Inhibiting αvβ8-mediated TGF-β activation blocks immunosuppressive regulatory T cell differentiation, which is a potential therapeutic strategy in cancer. The antibody is developed against Integrin αvβ8.

Species Reactivity

Human

Host Species

Mouse

Clone Number

11D12v2

Applications

Inhib; Block; In Vitro
Target

Target

Integrin αvβ8
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