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Creative Biolabs

HOT NeuroMab™ Anti-Integrin αvβ8 BBB Shuttle Antibody(NRZP-1222-ZP1218)

[CAT#: NRZP-1222-ZP1218]

Host Species:
Mouse
Species Reactivity:
Human
Applications:
Inhib; Block; In Vitro

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Product Overview

Description

Integrin αvβ8 binds with exquisite specificity to latent transforming growth factor-β (L-TGF-β). Inhibiting αvβ8-mediated TGF-β activation blocks immunosuppressive regulatory T cell differentiation, which is a potential therapeutic strategy in cancer. The antibody is developed against Integrin αvβ8.

Species Reactivity

Human

Host Species

Mouse

Applications

Inhib; Block; In Vitro

Relevant Diseases

Epilepsy
Target

Target

Integrinαvβ8
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