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Creative Biolabs
Product

NeuroMab™ Anti-JIP-2/IB-2, Clone N135/37 (CBP8281)

[CAT#: NRP-0422-P180]

Species Reactivity:
Mouse; Rat
Applications:
WB; IHC; ICC

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Product Overview

Immunogen

Fusion protein amino acids 226-421 of mouse JIP-2/IB-2 (also known as C-junamino-terminal kinase-interacting protein 2, JNK-interacting protein 2, JNK MAP kinase scaffold protein 2, Islet-brain-2 and Mitogen-activated protein kinase 8-interacting protein 2, accession number Q9ERE9)
Rat: 94% identity (127/135 amino acids identical)
Human: 86% identity (173/200 amino acids identical)
>50% identity with JIP-1

Species Reactivity

Mouse; Rat

Clonality

Monoclonal

Isotype

IgG1

Clone Number

CBP8281

Applications

WB; IHC; ICC

Application Notes

Does not cross-react with JIP-1/IB-1

Conjugation

Unconjugated
Product Properties

Research Use Only

For reseaech use only, not for human or dignostic use.
Target

Target

MAPK8IP2

Official Name

MAPK8IP2

Full Name

JIP-2/IB-2

Alternative Names

MAPK8IP2; IB-2; IB2; JIP2; PRKM8IPL; mitogen-activated protein kinase 8 interacting protein 2

Uniprot ID

Q9ERE9
Product Pictures
IB

Fig. 1 Immunoblot versus extracts from various WT (+/+) and IB2 KO (-/-) mouse brain regions probed with N135/37.

IB

Fig. 2 tissue and transfected cell immunoblot: extracts of adult rat brain membrane RBM and COS cells transiently transfected with Flagtagged JIP-1, JIP-2 or untagged Kv2.1 plasmid and probed with N135/37 (left), mouse anti-Flag (middle) and N52A/42 (right).

IHC

Fig. 3 Adult rat brain immunohistochemistry.

IB

Fig. 4 Adult rat brain membrane immunoblot.

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