Creative Biolabs

Rat Anti-IL-10 Monoclonal Antibody (N12G8) Low Endotoxin, Unconjugated

[CAT#: NAB2007FY881]

Rat Monoclonal [N12G8] to IL-10

Host Species:
Rat
Species Reactivity:
Human
Applications:
ELISA; FuncS; IHC-P; WB

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Description
Rat anti-human interleukin 10 antibody, recognizes human interleukin 10 (IL-10). IL-10 is expressed by activated CD8 + peripheral blood T cells, activated T helper CD4 + T cell clones, mast cells, B cell lymphomas, and LPS activated monocytes. According to reports, the rat anti-human interleukin-10 antibody JES3-12G8 clone can neutralize the effect of IL-10.
Immunogen
Human IL-10 is expressed by COS cells.
Species Reactivity
Human
Clonality
monoclonal
Host Species
Rat
Isotype
IgG2a
Clone Number
N12G8
Applications
ELISA; FuncS; IHC-P; WB
Application Notes
WB: 1/100-1/250, IHC: 1/100
optimal dilutions for assays should be determined by the user.
Relevant Diseases
Amyotrophic Lateral Sclerosis; Frontotemporal Dementia
Conjugation
Unconjugated
Form
Liquid
Formulation
PBS
Preservatives
BSA free
Concentration
1 mg/ml
Purification
Protein G
Endotoxin Level
Low Endotoxin
Shipping
The product is shipped at 4°C. Upon receipt, store it immediately at the temperature recommended below.
Storage
Store at -20°C only. Storage in frost-free freezers is not recommended. This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend micr°Centrifugation before use.
Research Use Only
For research use only, not for diagnostic or therapeutic use.
Target
IL-10
Official Name
IL10
Full Name
Interleukin 10
Alternative Names
Interleukin 10
Gene ID
3586(Human)
Uniprot ID
P22301(Human)
1. Burdin, N. et al. (1993) Epstein-Barr virus transformation induces B lymphocytes to produce human interleukin 10.
2. Yssel, H. et al. (1992) IL-10 is produced by subsets of human CD4+ T cell clones and peripheral blood T cells.
3. Abrams, J.S. et al. (1992) Strategies of anti-cytokine monoclonal antibody development: immunoassay of IL-10 and IL-5 in clinical samples.
For Research Use Only. Not For Clinical Use.
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