Product
Mouse Anti-SERPINA3 Monoclonal Antibody (CBP6828)
[CAT#: NAB2007FY1777]
Alzheimer's disease (AD), amyotrophic lateral
sclerosis (ALS), Lewy body dementia (LBD),
- Host Species:
- Mouse
- Species Reactivity:
- Human
- Applications:
- IHC
Certificate of Analysis Lookup
To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number
To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number
SPECIFIC INQUIRY
inquiryProduct Overview
Description
Neuroinflammatory process is a key pathogenic factor Brain and spinal cord injury in the back. This applies not only to Acute brain injury and hypoxic-ischemic brain injury Stroke, but also used for chronic infections and neurodegenerative diseases Diseases such as Alzheimer's disease (AD), amyotrophic lateral cord Sclerosis (ALS), Lewy Body Dementia (LBD) and Multiple Sclerosis (Multiple sclerosis). In addition, local inflammation around the tumor also plays a role In the clinical progression and malignancy of glioblastoma, The most aggressive primary brain tumor. α1-Antichymotrypsin (symbol α1AC, A1AC or a1ACT) is an alpha globulin glycoprotein and a member of the superfamily of serine protease inhibitors. In humans, it is encoded by the SERPINA3 gene.
α1-Antichymotrypsin can inhibit the activity of certain enzymes called proteases by cutting them into different shapes or conformations, such as cathepsin G found in neutrophils and mast cells Chymase. This activity can protect certain tissues, such as the lower respiratory tract, from damage by proteolytic enzymes.
This protein is produced in the liver and is an acute phase protein induced during inflammation.
α1-Antichymotrypsin can inhibit the activity of certain enzymes called proteases by cutting them into different shapes or conformations, such as cathepsin G found in neutrophils and mast cells Chymase. This activity can protect certain tissues, such as the lower respiratory tract, from damage by proteolytic enzymes.
This protein is produced in the liver and is an acute phase protein induced during inflammation.
Epitope
Binds to an located within the peptide sequence QDKMEEVEAMLLPET
Species Reactivity
Human
Clonality
Monoclonal
Host Species
Mouse
Isotype
IgG1
Clone Number
CBP6828
Applications
IHC
Application Notes
IHC: 1:2500-1:5000
Relevant Diseases
Neuroinflammation; Neurodegenerative Disease; Alzheimer's Disease; Amyotrophic Lateral Sclerosis; Lewy body dementia
Research Areas
Neuroinflammation; Neurodegeneration
Product Properties
Form
Liquid
Formulation
PBS, pH 7.2, 40% glycerol
Preservatives
0.02% Sodium azide
Concentration
1 mg/ml
Purification
Protein A purified
Shipping
Gel Pack
Storage
Store at +4°C for short term storage. Long time storage is recommended at -20°C.
Handling Advice
The antibody solution should be gently mixed before use.
Research Use Only
For research use only
Target
Publications
Publications (0)
Neural Antibodies
Neural Genes
Kits
Neural Cell Lines
For Research Use Only. Not For Clinical Use.
