Product
NeuroMab™ Anti-NRP1B BBB Shuttle Antibody, Clone MNRP1685A
[CAT#: NRZP-1022-ZP3289]
- Host Species:
- Human
- Species Reactivity:
- Human
- Applications:
- IHC; ELISA; Inhib; In Vitro; In Vivo; Antagonist
Certificate of Analysis Lookup
To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number
To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number
SPECIFIC INQUIRY
inquiryProduct Overview
Description
Brain uptake of therapeutic antibodies is severely limited by their size. To achieve enhanced BBB crossing, Creative Biolabs developed a BBB shuttle antibody platform by utilizing the endogenous macromolecule transportation pathway, known as receptor-mediated transcytosis (RMT). The engineered antibody-based carrier is believed to significantly to increase the macromolecule brain entry to combat CNS diseases.
Notes: The BBB antibody is made-to order and available in a customized format. Please don't hesitate contact us for more details.
Notes: The BBB antibody is made-to order and available in a customized format. Please don't hesitate contact us for more details.
Species Reactivity
Human
Clonality
Monoclonal
Host Species
Human
Clone Number
MNRP1685A
Applications
IHC; ELISA; Inhib; In Vitro; In Vivo; Antagonist
Product Properties
Storage
Store at -20°C. Do not aliquot the antibody.
Research Use Only
For research use only
Target
Target
NRP1B
Official Name
NRP1B
Alternative Names
Neuropilin
Product Pictures
PK
Figure 1 shows the pharmacokinetic data for MNRP1685A.
FuncS
Figure 2 is a graph showing data on infusion-related symptoms.
FuncS
Figure 3 is a graph showing P1GF as a pharmacodynamic marker of systemic NRP1 pathway inhibition.
FuncS
Figure 4 is a graph showing the time of patient participation in the study.
Publications
Publications (0)
Neural Antibodies
For Research Use Only. Not For Clinical Use.
