Product
NeuroMab™ Anti-pan-Neurofascin BBB Shuttle Antibody, Clone L11A/41
[CAT#: NRZP-0423-ZP327]
- Species Reactivity:
- Human; Rat
- Applications:
- WB; IHC; IP; ICC
Certificate of Analysis Lookup
To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number
To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number
SPECIFIC INQUIRY
inquiryProduct Overview
Description
The BBB is a highly selective membrane that surrounds the blood vessels in the brain, and it can prevent many molecules, including potentially life-saving drugs, from entering the brain. The anti-Pan-Neurofascin BBB Shuttle Antibody is designed to bind to receptors on the surface of cells in the BBB, and once bound, the antibody can cross the BBB and into the brain. This technology has the potential to revolutionize the treatment of brain disorders by enabling drugs to reach the brain more effectively.
Immunogen
Fusion protein 1066-1174 (intracellular domain common to NF-155 and NF-186) of rat NF-155 (accession number AAL27854)
Human: 99% identity (108/109 amino acids identical)
Mouse=99% identity (108/109 amino acids identical)
Human: 99% identity (108/109 amino acids identical)
Mouse=99% identity (108/109 amino acids identical)
Construction
We offer several options for BBB shuttle antibody design. Antibody construction can be customized according to customer requirements.
Species Reactivity
Human; Rat
Clonality
Monoclonal
Isotype
IgG1
Clone Number
L11A/41
Applications
WB; IHC; IP; ICC
Research Areas
CAMs
Conjugation
Unconjugated
Product Properties
Research Use Only
For reseaech use only, not for human or dignostic use.
Target
Target
Pan-Neurofascin
Official Name
Pan-Neurofascin
Full Name
Pan-Neurofascin
Alternative Names
NFASC; NF; NRCAML; neurofascin; NEDCPMD
Product Pictures
IF
Fig. 1 Adult rat optic nerve immunofluorescence staining L11A/41 (5 µg/ml)=red Rabbit anti-Caspr=green.
IB
Fig. 2 Adult rat brain membrane immunoblot.
Publications
Publications (0)
For Research Use Only. Not For Clinical Use.
