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Creative Biolabs
Product

NeuroMab™ Anti-Pan-Neurofascin (CBP8429)

[CAT#: NRP-0422-P328]

Species Reactivity:
Human; Rat
Applications:
WB; IHC; ICC

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Product Overview

Immunogen

Lipid raft fractions isolated from adult rat brain. Target identified as Neurofascin by:
-binding to NF-186-tranfected COS cells
-recognition of NF155 and NF186 but not other highly related L1 CAMs like NrCAM
-immunoprecipitation of NF155 and NF186 and confirmation by mass spectrometry
-loss of immunostaining against NF186-shRNA knockdown samples
Rat: amino acids 25-1110 (extracellular domain common to NF155 and NF186)
Mouse: 98% identity (1074/1086 amino acids identical)
Human: 79% identity (955/1195 amino acids identical)

Species Reactivity

Human; Rat

Clonality

Monoclonal

Isotype

IgG2a

Clone Number

CBP8429

Applications

WB; IHC; ICC

Research Areas

CAMs

Conjugation

Unconjugated
Product Properties

Research Use Only

For reseaech use only, not for human or dignostic use.
Target

Target

Pan-Neurofascin

Official Name

Pan-Neurofascin

Full Name

Pan-Neurofascin (extracellular)

Alternative Names

NFASC; NF; NRCAML; neurofascin; NEDCPMD
Product Pictures
IB

Fig. 1 Immunoblot on crude membrane fractions from whole mouse (MBM) and rat (RBM) brain and from human hippocampus [HBM(H)], cerebral cortex [HBM(Cx)] and cerebellum [HBM(Cb)] probed with A12/18 (left) and N52A/42 (right) TC supe.

IHC

Fig. 1 Adult rat brain immunohistochemistry.

IB

Fig. 3 Adult rat brain membrane immunoblot.

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