Human CHO-K1/M3 Stable Cell Line

[CAT#: NCL20120009CR]

Muscarinic Acetylcholine Receptor M3 Stable Cell Line

Species:: Human

Applications:: GPCR Screening

Cell Types:: Other Cells

Certificate of Analysis Lookup
To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number

Request Pricing

Inquiry

Product Overview

Description

Muscarinic acetylcholine receptors can interact with G-proteins to initiate intracellular responses. Five muscarinic receptor subtypes have been identified and named from M1 to M5. The M2 muscarinic receptor couples to Gi/o to inhibit cAMP production.

Cell Types

Other Cells

Applications

GPCR Screening

Research Areas

GPCR

Species

Human

Properties

Size

>1x10^6 Cells

Form

Frozen cells

Culture Medium

Ham's F12, 10% FBS, 400 μg/ml G418

Freeze Medium

45% culture medium, 45% FBS, 10% DMSO

Receptor

M3/CHRM3

Family

Acetylcholine receptor (muscarinic)

Strain

M3 Cell Line

Cell Purity

>95%

Shipping

Dry ice

Storage

Liquid nitrogen immediately upon delivery

Handling Advice

Avoid inhalation. Avoid contact with eyes, skin, and clothing. Avoid prolonged or
repeated exposure.

Research Use Only

For research use only, not for diagnostic or therapeutic use.

Warnings

Store under recommended storage conditions (liquid nitrogen). Do not expose to high temperature. After expiration, discard all remaining reagents.

Target Details

Target

CHRM3

Official Name

CHRM3

Alternative Names

M3 receptor; m3; HM4; acetylcholine receptor; muscarinic 3; cholinergic receptor; muscarinic 3; cholinergic receptor; muscarinic 3; cardiac; muscarinic acetylcholine receptor M3; M3R; Chrm-3; muscarinic acetylcholine receptor 3

Gene ID

1131(Human); 12671(Mouse); 24260(Rat)

Uniprot ID

P20309(Human); Q9ERZ3(Mouse); P08483(Rat)

References

1. Mi, G., Liu, S., Zhang, J., Liang, H., Gao, Y., Li, N.,.. & Yang, Z. (2017). Levo-tetrahydroberberrubine produces anxiolytic-like effects in mice through the 5-HT 1A receptor. PloS one, 12(1), e0168964.

Publications