Product
Human CHO-K1/M3 Stable Cell Line
[CAT#: NCL20120009CR]
Muscarinic Acetylcholine Receptor M3 Stable Cell Line
- Species:
- Human
- Applications:
- GPCR Screening
- Cell Types:
- CHO-K1; GPCR Cell
Certificate of Analysis Lookup
To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number
To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number
Product Overview
Description
Muscarinic acetylcholine receptors can interact with G-proteins to initiate intracellular responses. Five muscarinic receptor subtypes have been identified and named from M1 to M5. The M2 muscarinic receptor couples to Gi/o to inhibit cAMP production.
Cell Types
CHO-K1; GPCR Cell
Applications
GPCR Screening
Research Areas
GPCR
Species
Human
Properties
Size
>1x10^6 Cells
Form
Frozen cells
Culture Medium
Ham's F12, 10% FBS, 400 μg/ml G418
Freeze Medium
45% culture medium, 45% FBS, 10% DMSO
Receptor
M3/CHRM3
Family
Acetylcholine receptor (muscarinic)
Strain
M3 Cell Line
Cell Purity
>95%
Shipping
Dry ice
Storage
Liquid nitrogen immediately upon delivery
Handling Advice
Avoid inhalation. Avoid contact with eyes, skin, and clothing. Avoid prolonged or
repeated exposure.
repeated exposure.
Research Use Only
For research use only, not for diagnostic or therapeutic use.
Warnings
Store under recommended storage conditions (liquid nitrogen). Do not expose to high temperature. After expiration, discard all remaining reagents.
Target Details
Target
CHRM3
Official Name
CHRM3
Alternative Names
M3 receptor; m3; HM4; acetylcholine receptor; muscarinic 3; cholinergic receptor; muscarinic 3; cholinergic receptor; muscarinic 3; cardiac; muscarinic acetylcholine receptor M3; M3R; Chrm-3; muscarinic acetylcholine receptor 3
References
1. Mi, G., Liu, S., Zhang, J., Liang, H., Gao, Y., Li, N.,.. & Yang, Z. (2017). Levo-tetrahydroberberrubine produces anxiolytic-like effects in mice through the 5-HT 1A receptor. PloS one, 12(1), e0168964.
Publications
Publications (0)
Neural Cell Lines
For Research Use Only. Not For Clinical Use.
