Creative Biolabs

Human CHO-K1/M5 Stable Cell Line

[CAT#: NCL20120011CR]

Muscarinic Acetylcholine Receptor M5 Stable Cell Line

Species:
Human
Applications:
GPCR Screening
Cell Types:
CHO-K1; GPCR Cell

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Description
Muscarinic acetylcholine receptors can interact with G-proteins to initiate intracellular responses. Five muscarinic receptor subtypes have been identified and named from M1 to M5. The M2 muscarinic receptor couples to Gi/o to inhibit cAMP production.
Cell Types
CHO-K1; GPCR Cell
Applications
GPCR Screening
Relevant Diseases
Neurological Disorders
Research Areas
GPCR; Neural Signal Transduction
Species
Human
Size
2 vials
Form
Frozen cells
Culture Medium
Ham's F12, 10% FBS, 200 μg/ml Zeocin
Freeze Medium
45% culture medium, 45% FBS, 10% DMSO
Receptor
M5/CHRM5
Family
Acetylcholine receptor (muscarinic)
Strain
M5 Cell Line
Cell Purity
>95%
Shipping
Dry ice
Storage
Liquid nitrogen immediately upon delivery
Handling Advice
Avoid inhalation. Avoid contact with eyes, skin, and clothing. Avoid prolonged or
repeated exposure.
Research Use Only
For research use only, not for diagnostic or therapeutic use.
Warnings
Store under recommended storage conditions (liquid nitrogen). Do not expose to high temperature. After expiration, discard all remaining reagents.
Target
CHRM5
Official Name
CHRM5
Alternative Names
M5 receptor; m5; acetylcholine receptor; muscarinic 5; cholinergic receptor; muscarinic 5; muscarinic acetylcholine receptor M5; muscarinic acetylcholine receptor 5; M5R
1. Montagna, E., Crux, S., Luckner, M., Herber, J., Colombo, A. V., Marinković, P.,.. & Sgobio, C. (2019). In vivo Ca2+ imaging of astrocytic microdomains reveals a critical role of the amyloid precursor protein for mitochondria. Glia, 67(5), 985-998. 2. Xu, Y., Wu, X., Wang, S., Yang, C., Li, Y., & Cao, Y. (2019). Hydroxyapatite Nanoparticle-Crosslinked Peptide Hydrogels for Three-Dimensional Culture and Differentiation of MC3T3-E1 Osteoblasts. Journal of biomedical nanotechnology, 15(12), 2351-2362. 3. Lan, J., Rollins, J. A., Zang, X., Wu, D., Zou, L., Wang, Z.,.. & Chen, D. (2019). Translational regulation of non-autonomous mitochondrial stress response promotes longevity. Cell reports, 28(4), 1050-1062.
For Research Use Only. Not For Clinical Use.
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