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Creative Biolabs

NeuroMab™ Anti-Transferrin Receptor BBB Shuttle Antibody(NRZP-1022-ZP3954)

[CAT#: NRZP-1022-ZP3954]

Host Species:
Mouse
Species Reactivity:
Human; Cynomolgus Monkey
Applications:
ADCC; ELISA; In Vitro

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Product Overview

Description

Brain uptake of therapeutic antibodies is severely limited by their size. To achieve enhanced BBB crossing, Creative Biolabs developed a BBB shuttle antibody platform by utilizing the endogenous macromolecule transportation pathway, known as receptor-mediated transcytosis (RMT). The engineered antibody-based carrier is believed to significantly to increase the macromolecule brain entry to combat CNS diseases.
Notes: The BBB antibody is made-to order and available in a customized format. Please don't hesitate contact us for more details.

Species Reactivity

Human; Cynomolgus Monkey

Clonality

Monoclonal

Host Species

Mouse

Applications

ADCC; ELISA; In Vitro

Relevant Diseases

Parkinson's Disease; Amyotrophic Lateral Sclerosis; Huntington's Disease; Multiple Sclerosis; Tumor
Product Properties

Storage

Store at -20°C. Do not aliquot the antibody.

Research Use Only

For research use only
Target

Target

TransferrinReceptor

Official Name

TfR

Full Name

Transferrin Receptor

Alternative Names

CD71; TFR1
Publications

Publications (0)

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For Research Use Only. Not For Clinical Use.
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