Multiple Sclerosis Related Antibodies
Multiple sclerosis (MS) is a chronic inflammatory and demyelinating disease of the central nervous system (CNS). The spatial and temporal multiplicity of lesions are the prominent features of this disease. Most MS patients begin with relapsing-remitting MS (RRMS), which develops into secondary progressive MS (SPMS) with increased clinical exacerbations. MS may be caused by genetic susceptibility, environment, lifestyle, viral infection and immune mechanisms. The above causes urgently need further research and large sample randomized controlled clinical trials to verify. Clarifying the cause and pathogenesis of MS will be the focus of future research.
Key Factors of MS
- Myelin sheath: The immune system mistakenly attacks the myelin sheath, a protective covering of nerve fibers in the central nervous system. Targeting this process can help prevent further damage to nerve cells. These include MBP, myelin-associated glycoprotein (MAG), MOG, PLP, CRYAB, and oligodendrocyte-specific protein.
Cat. No | Product Name | Host | Application |
---|---|---|---|
NAB2007FY251 | Mouse Anti-MBP Monoclonal Antibody (CBP1514) | Monoclonal | ELISA; RIA |
NAB2007FY254 | Rat Anti-MBP Monoclonal Antibody (CBP1568) | Monoclonal | ELISA; IF; IHC-Fr |
NAB-08-PZ797 | NeuroMab™ Rabbit Anti-MBP Monoclonal Antibody (CBP1900) | Monoclonal | WB; IHC-P; IHC-Fr |
NAB-0720-Z9019 | Human Anti-MBP Monoclonal Antibody (CBP7047) | Monoclonal | ELISA; WB; ICC; IF; IHC-P |
Cat. No | Product Name | Host | Application |
---|---|---|---|
NAB-0720-Z3221 | NeuroMab™ Rabbit Anti-MAG Monoclonal Antibody (CBP831) | Monoclonal | WB; IP; FC |
NAB-08-PZ738 | Mouse Anti-MAG Monoclonal Antibody (CBP1888) | Monoclonal | FC; WB |
NAB2010216LS | Rat Anti-MAG Monoclonal Antibody (CBP2283) | Monoclonal | WB; IHC-P |
Cat. No | Product Name | Host | Application |
---|---|---|---|
NAB-2103-P484 | NeuroMab™ Mouse Anti-MOG Monoclonal Antibody (CBP4840) | Monoclonal | WB; IP; IF; IHC-P; ELISA |
NRZP-0922-ZP3346 | NeuroMab™ Anti-MOG Antibody, Clone N28034 (CBP14657) | Monoclonal | WB; IHC |
NAB-0720-Z3238 | Mouse Anti-MOG Monoclonal Antibody (CBP838) | Monoclonal | WB; IHC-P |
Cat. No | Product Name | Host | Application |
---|---|---|---|
NAB2007FY1770 | Mouse Anti-PLP1 Monoclonal Antibody (CBP6821) | Monoclonal | IHC |
NAB-0720-Z9031 | NeuroMab™ Rabbit Anti-PLP Monoclonal Antibody (CBP7053) | Monoclonal | IHC-P; IP |
NAB-0720-Z9037 | Mouse Anti-PLP Monoclonal Antibody (CBP7056) | Monoclonal | IHC-Fr; WB; ICC; IF; IHC |
- Immune cells: MS' immunological response is mediated by specific immune cell types. Targeting these immune cells can help regulate the immune system and protect nerve cells. These cells include T cells, B cells, microglia, macrophages, and dendritic cells.
Cat. No | Product Name | Host | Application |
---|---|---|---|
NAB20101932CR | Mouse Anti-IBA1 Monoclonal Antibody (CBP2855) | Monoclonal | IHC; ELISA |
NAB-2103-P418 | NeuroMab™ Mouse Anti-IBA1 Monoclonal Antibody (CBP4798) | Monoclonal | WB; IP; IF; IHC-P; FC |
NRZP-0722-ZP500 | NeuroMab™ Anti-Human AIF-1/Iba1 Antibody, Clone 603102 (CBP9068) | Monoclonal | IHC |
- Neuroinflammation: Neuroinflammation is a significant factor in the progression of MS. Targeting inflammatory pathways can help alleviate symptoms and avoid relapses. These include pro- and anti-inflammatory cytokines secreted by microglia, macrophages and dendritic cells.
If you require further information about MS-related antibodies, please click on the related products below or contact us directly. We will respond to your query as soon as possible.
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