Immortalized Cell Lines

Cell immortalization refers to the process in which cells cultured in vitro break free from the limits of cellular spontaneous senescence, acquire the ability to proliferate indefinitely under the influence of external factors. Cells derived from normal tissues can divide and grow under typical in vitro culture conditions, but after a limited number of passages, they stop proliferating, undergo aging, and eventually die. By introducing exogenous immortalizing genes into target cells through techniques such as gene transfection, immortalized cell lines can be established to make cultured cells proliferative and homogeneous. In-depth research on cell immortalization is not only beneficial for understanding the molecular mechanisms of cell proliferation and aging but also lays a solid foundation for exploring cancer therapy and organ transplantation research. Additionally, immortalized cells can be passaged multiple times, providing researchers with a valuable resource for various cell models and facilitating scientific research.

In addition to providing a comprehensive range of widely used immortalized cell lines, Creative Biolabs has many years of experience in cell immortalization services and has successfully established a variety of immortalized cell lines, including those sourced from humans, mice, rats, and rabbits.

Cell Immortalization Methods

Mammalian cells can be immortalized using several methods. Among them, induction of cell immortalization by SV40 T antigen and hTERT virus is the simplest and most reliable, widely used.

Advantages

With Creative Biolabs, you can effortlessly obtain excellent immortalized cell products.

Well-identified

STR identification

Species identification

Immunofluorescence identification

High Quality

Passages number ≤5

Cell viability >90%

Cell number ≥1×10⁶ cells/vial

Trending Products

Creative Biolabs is dedicated to providing reliable immortalized cell lines to speed up your neuroscience research.

Cat. No.	Product Name	Cat. No.	Product Name
NCL-2105-P182-AM	Human Astrocytes, Immortalized	NCL2110P154	Mouse Retinal Ganglion Cell Line RGC-5
NCL-21P6-221	Rat Cerebellar Granule Cell Line, Immortalized	NCL2110P059	Mouse Midbrain Dopaminergic Neuron Cell MN9D
NCL2110P073	Mouse Microglia N9, Immortalized	NCL2110P206	Immortalized Human Microglia
NCL2110P153	Mouse Microglia Cell Line BV-2, Immortalized	NCL-2108P38	Human Microglia Cell Line HMC3, Immortalized
NCL-2108P34	Human Glial (Oligodendrocytic) Hybrid Cell Line (MO3.13)	NCL2110P015	Rat Microglia Cell Line HAPI, Immortalized
NCL-2108-P020	Immortalized Human Cerebral Microvascular Endothelial Cells	NCL-2105-P201-AM	Mouse Brain Endothelial Cells - SV40, Immortalized
NCL2110P098	Mouse Dendritic Cell DC2.4	NCL-2108P21	Rat Schwann Cells RSC96, Immortalized
NCL-21P6-192	Rat Retinal Muller Cell Line, Immortalized	NCL-2106-S93	Rat Immortalized Retinal Muller Cell Line rMC-1
NCL-21P6-177	Immortalized Human Alveolar Epithelial Cell Line	NCL-21P6-176	Mouse Kupffer Cell Line (ImKC), Immortalized