Immortalized Cell Products
Cell immortalization refers to the process in which cells cultured in vitro break free from the limits of cellular spontaneous senescence, acquire the ability to proliferate indefinitely under the influence of external factors. Cells derived from normal tissues can divide and grow under typical in vitro culture conditions, but after a limited number of passages, they stop proliferating, undergo aging, and eventually die. By introducing exogenous immortalizing genes into target cells through techniques such as gene transfection, immortalized cell lines can be established to make cultured cells proliferative and homogeneous. In-depth research on cell immortalization is not only beneficial for understanding the molecular mechanisms of cell proliferation and aging but also lays a solid foundation for exploring cancer therapy and organ transplantation research. Additionally, immortalized cells can be passaged multiple times, providing researchers with a valuable resource for various cell models and facilitating scientific research.
In addition to providing a comprehensive range of widely used immortalized cell lines, Creative Biolabs has many years of experience in cell immortalization services and has successfully established a variety of immortalized cell lines, including those sourced from humans, mice, rats, and rabbits.
Cell Immortalization Methods
Mammalian cells can be immortalized using several methods. Among them, induction of cell immortalization by SV40 T antigen and hTERT virus is the simplest and most reliable, widely used.
Advantages
With Creative Biolabs, you can effortlessly obtain excellent immortalized cell products.
Well-identified
STR identification
Species identification
Immunofluorescence identification
High Quality
Passages number ≤5
Cell viability >90%
Cell number ≥1×106 cells/vial
Trending Products
Creative Biolabs is dedicated to providing reliable immortalized cell lines to speed up your neuroscience research.
| Cat. No. | Product Name | Cat. No. | Product Name |
| NCL-21P6-221 | Rat Cerebellar Granule Cell Line, Immortalized | NCL2110P059 | Mouse Midbrain Dopaminergic Neuron Cell MN9D |
| NCL2110P073 | Mouse Microglia N9, Immortalized | NCL2110P206 | Immortalized Human Microglia |
| NCL2110P153 | Mouse Microglia Cell Line BV-2, Immortalized | NCL-2108P38 | Human Microglia Cell Line HMC3, Immortalized |
| NCL-2108P34 | Human Glial (Oligodendrocytic) Hybrid Cell Line (MO3.13) | NCL2110P015 | Rat Microglia Cell Line HAPI, Immortalized |
| NCL-2108-P020 | Immortalized Human Cerebral Microvascular Endothelial Cells | NCL-2105-P201-AM | Mouse Brain Endothelial Cells - SV40, Immortalized |
| NCL2110P098 | Mouse Dendritic Cell DC2.4 | NCL-2108P21 | Rat Schwann Cells RSC96, Immortalized |
| NCL-21P6-192 | Rat Retinal Muller Cell Line, Immortalized | NCL-2106-S93 | Rat Immortalized Retinal Muller Cell Line rMC-1 |
| NCL-21P6-177 | Immortalized Human Alveolar Epithelial Cell Line | NCL-21P6-176 | Mouse Kupffer Cell Line (ImKC), Immortalized |
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Mouse Retinal Ganglion Cell Line RGC-5 [CAT#: NCL2110P154]
- Species:
- Mouse
- Applications:
- Cell Culture
- Cell Types:
- Visual system-related Cells
Mouse Microglia Cell Line BV-2, Immortalized [CAT#: NCL2110P153]
- Species:
- Mouse
- Applications:
- Cell Culture
- Cell Types:
- Microglia
Mouse Microglia N9 [CAT#: NCL2110P073]
- Species:
- Mouse
- Applications:
- Cell Culture
- Cell Types:
- Microglia
Human Retinal Epithelial Cell ARPE-19 [CAT#: NCL2110P069]
- Species:
- Human
- Applications:
- Cell Culture
- Cell Types:
- Visual system-related Cells
Mouse Midbrain Dopaminergic Neuron Cell MN9D [CAT#: NCL2110P059]
- Species:
- Mouse
- Applications:
- Cell Culture
- Cell Types:
- Neurons
Rat Microglia Cell Line HAPI, Immortalized [CAT#: NCL2110P015]
- Species:
- Rat
- Applications:
- Cell Culture
- Cell Types:
- Microglia
Immortalized Human Cerebral Microvascular Endothelial Cells [CAT#: NCL-2108-P020]
Model of human blood-brain barrier
- Species:
- Human
- Cell Types:
- BBB-related Cells
Human Microglia Cell Line HMC3, Immortalized [CAT#: NCL-2108P38]
- Species:
- Human
- Applications:
- Cell Culture
- Cell Types:
- Microglia
Human Glial (Oligodendrocytic) Hybrid Cell Line (MO3.13) [CAT#: NCL-2108P34]
- Species:
- Human
- Applications:
- Cell Culture
- Cell Types:
- Tumor Cells
Rat Schwann Cells RSC96, Immortalized [CAT#: NCL-2108P21]
- Species:
- Rat
- Applications:
- Cell Culture
- Cell Types:
- Schwann Cells
Rat Retinal Muller Cell Line, Immortalized [CAT#: NCL-21P6-192]
Immortalized Cell Lines
- Species:
- Rat
- Applications:
- Cell Culture
- Cell Types:
- Visual system-related Cells
Rat Immortalized Retinal Muller Cell Line rMC-1 [CAT#: NCL-2106-S93]
- Species:
- Rat
- Cell Types:
- Visual system-related Cells
Human Astrocytes, Immortalized [CAT#: NCL-2105-P182-AM]
Positive for GFAP
- Species:
- Human
- Cell Types:
- Astrocytes
- Species:
- Human
- Cell Types:
- Astrocytes
- Species:
- Human
- Cell Types:
- Other Cells
- Species:
- Human
- Cell Types:
- Tumor Cells
- Species:
- Human
- Cell Types:
- Visual system-related Cells
- Species:
- Human
- Cell Types:
- BBB-related Cells
- Species:
- Human
- Cell Types:
- BBB-related Cells
- Species:
- Human
- Cell Types:
- BBB-related Cells
- Species:
- Human
- Cell Types:
- BBB-related Cells
Fluorescent Immortalized Primary Cells
- Species:
- Human
- Applications:
- Cell Culture
- Cell Types:
- Microglia
Fluorescent Immortalized Primary Cells
- Species:
- Human
- Applications:
- Cell Culture
- Cell Types:
- Microglia
Fluorescent Immortalized Primary Cells
- Species:
- Human
- Applications:
- Cell Culture
- Cell Types:
- BBB-related Cells
Fluorescent Immortalized Primary Cells
- Species:
- Human
- Applications:
- Cell Culture
- Cell Types:
- BBB-related Cells
- Species:
- Human
- Applications:
- Cell Culture
- Cell Types:
- Visual system-related Cells
- Species:
- Human
- Species:
- Human
- Applications:
- Cell Culture
- Cell Types:
- Visual system-related Cells
- Species:
- Human
- Applications:
- Cell Culture
- Cell Types:
- Visual system-related Cells
- Species:
- Human
- Applications:
- Cell Culture
- Cell Types:
- Visual system-related Cells
- iNeuMab™ Mouse Anti-SHANK3 Monoclonal Antibody (CBP929) (Cat#: NAB-0720-Z3477)
- Mouse Anti-Human α-Synuclein Phospho (Tyr39) (CBP3706) (Cat#: NAB201250LS)
- iNeuMab™ Mouse Anti-LRP1 Monoclonal Antibody (CBP3363) (Cat#: NAB-0720-Z6479)
- iNeuMab™ Rabbit Anti-Alpha-synuclein (CBP1631) (Cat#: NAB-08-PZ079)
- iNeuMab™ Rabbit Anti-LRRK2 Monoclonal Antibody (CBP1887) (Cat#: NAB-08-PZ735)
- iNeuMab™ Mouse Anti-EFNB2 Monoclonal Antibody (CBP1159) (Cat#: NAB-0720-Z4396)
- iNeuMab™ Anti-F-Spondin/SPON1 Antibody, Clone 3F4 (Cat#: NRZP-0822-ZP4740)
- Mouse Anti-SCN5A Monoclonal Antibody (CBP708) (Cat#: NAB-0720-Z2720)
- Green Fluorescent Tau cell Line (Cat#: NCL2110P219)
- Rat Muller Cell (Cat#: NCL2110P040)
- Human Astrocytes (Cat#: NCC20-9PZ01)
- Human Brain Microvascular Endothelial Cells (Cat#: NCL-2103-P133)
- Rat Schwann Cells RSC96, Immortalized (Cat#: NCL-2108P21)
- Mouse Microglia from C57BL/6 (Cat#: NCL-21P6-082)
- Rat Olfactory Ensheathing Cells (Cat#: NRZP-1122-ZP162)
- iNeu™ Human Oligodendrocyte Progenitor Cells (OPCs) (Cat#: NCL-2103-P49)
- Mouse Glioma Cell Line GL-261-Luc (Cat#: NCL-2108P06)
- Rat Glioma Cell Line C6 (Cat#: NCL2110P346)
- Human GFAP ELISA Kit [Colorimetric] (Cat#: NPP2011ZP383)
- Human Tau Aggregation Kit (Cat#: NRP-0322-P2173)
- Alpha Synuclein Aggregation Kit (Cat#: NRZP-1122-ZP15)
- Amyloid beta 1-42 Kit (Cat#: NRP-0322-P2170)
- Human Poly ADP ribose polymerase,PARP Assay Kit (Cat#: NRZP-1122-ZP62)
- Alpha-Synuclein Aggregation Assay Kit (Cat#: NRZP-1122-ZP37)
- Beta Amyloid (1-40), Aggregation Kit (Cat#: NRZP-0323-ZP199)
- Beta Amyloid (1-42), Aggregation Kit (Cat#: NRZP-0323-ZP200)
- AAV2 Full Capsids, Reference Standards (Cat#: NTC2101070CR)
- Dextran, NHS Activated (Cat#: NRZP-0722-ZP124)
- VSV-eGFP (Cat#: NTA-2011-ZP20)
- Lenti of Mouse synuclein, alpha (Snca) transcript variant (NM_001042451) ORF clone, mGFP Tagged (Cat#: NEP-0521-R0864)
- Rat Parkinson disease (autosomal recessive, juvenile) 2, parkin (Park2) (NM_020093) ORF clone/lentiviral particle, Myc-DDK Tagged (Cat#: NEP-0621-R0041)
- ABCA1 Antisense Oligonucleotide (NV-2106-P27) (Cat#: NV-2106-P27)
- Mouse SOD1 shRNA Silencing Adenovirus (Cat#: NV-2106-P14)
- Tau Antisense Oligonucleotide (IONIS-MAPTRx) (Cat#: NV-2106-P29)
- Human superoxide dismutase 3, extracellular (SOD3) (NM_003102) ORF clone, Untagged (Cat#: NEP-0521-R0808)
- Human presenilin 1 (PSEN1), transcript variant 2 (NM_007318) ORF clone, TurboGFP Tagged (Cat#: NEP-0421-R0140)
- Mouse Parkinson disease (autosomal recessive, early onset) 7 (Park7) (NM_020569) clone, Untagged (Cat#: NEP-0621-R0133)
- Human huntingtin-associated protein 1 (HAP1) transcript variant 2 (NM_177977) ORF clone, Myc-DDK Tagged (Cat#: NEP-0521-R0676)
- Human huntingtin (HTT) (NM_002111) ORF clone, Myc-DDK Tagged (Cat#: NEP-0521-R0497)
- NeuroBiologics™ Monkey Cerebrospinal Fluid (Cat#: NRZP-0822-ZP495)
- NeuroBiologics™ Rat Cerebrospinal Fluid (Cat#: NRZP-0822-ZP496)
- NeuroBiologics™ Human Cerebrospinal Fluid (Cat#: NRZP-0822-ZP491)
- NeuroBiologics™ Mouse Cerebrospinal Fluid (Cat#: NRZP-0822-ZP497)
- NeuroBiologics™ Pig Cerebrospinal Fluid (Cat#: NRZP-0822-ZP498)
- NeuroPro™ Anti-TNFR BBB Shuttle Protein (Cat#: NRZP-0423-ZP501)
- NeuroPro™ Anti-PON1 BBB Shuttle Protein (Cat#: NRZP-0423-ZP507)
- NeuroPro™ Anti-GDNF BBB Shuttle Protein (Cat#: NRZP-0423-ZP509)
- NeuroPro™ Anti-Erythropoietin BBB Shuttle Protein (Cat#: NRZP-0423-ZP499)
- NeuroPro™ Anti-SGSH BBB Shuttle Protein (Cat#: NRZP-0423-ZP505)
- NeuroPro™ Anti-ASA BBB Shuttle Protein (Cat#: NRZP-0423-ZP504)
- NeuroPro™ Anti-GDNF BBB Shuttle Protein (Cat#: NRZP-0423-ZP500)
- NeuroPro™ Anti-EPO BBB Shuttle Protein (Cat#: NRZP-0423-ZP508)
- NeuroPro™ Anti-IDS BBB Shuttle Protein (Cat#: NRZP-0423-ZP503)
- NeuroPro™ Anti-TNFR BBB Shuttle Protein (Cat#: NRZP-0423-ZP510)
