- Species:
- Human
- Applications:
- Cell Culture
- Cell Types:
- Microglia
To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
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Cell Types
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Growth Pattern
Morphology
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Handling Advice
Changing cell medium: 2~3 times/week
Research Use Only
Quality Control
• Cells are tested by PCR and are negative for Hepatitis A, B, C, HPV, Herpes and HIV-1 & 2 viruses.
• Cells are negative for mycoplasma contamination.
Publications (0)
ExcellentThe cells showed robust proliferation and maintained typical microglial morphologyImpressed with the HMC3 cell line's ability to mimic primary microglia behavior, essential for our investigations into Alzheimer's disease pathogenesis. The cells exhibited significant phagocytic activity and cytokine secretion patterns akin to activated microglia.
ExcellentExcellent compatibilityThe HMC3 cells demonstrated excellent compatibility with our imaging assays, allowing detailed visualization of microglial dynamics in response to various stimuli. Their consistent performance enabled high-content screening of anti-inflammatory compounds.
ExcellentStable phenotypeWe chose the HMC3 cell line for its well-documented transcriptomic profile resembling primary microglia. This authenticity facilitated accurate interpretation of RNA-seq data, aiding our studies on gene expression changes in neuroinflammatory conditions.
ExcellentGreat authenticity and suitabilityThe HMC3 cells' expression of key microglial markers validated their authenticity and suitability for immunocytochemical assays. Their consistent antigen expression patterns facilitated accurate characterization of microglial activation states.
ExcellentLeveraged cell line's phagocytic capacityWe leveraged the HMC3 cell line's phagocytic capacity to study its implications in neurodegenerative clearance mechanisms. The cells' efficient engulfment of fluorescent particles enabled quantitative analysis of phagocytic activity.
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