Neurotransmitter Sensors

Neurotransmitters are important "messengers" that carry information between synapses. Neurotransmitter disorders are often associated with various diseases. As a result, the detection and tracking of neurotransmitters is a critical step in the study of brain function and related diseases. Our neurotransmitter sensor has extremely high sensitivity, molecular specificity, precise spatial resolution and sub-second response time. It has been verified on more than a dozen types of neurons in the brains of drosophila, zebrafish and mice, making it an important tool for studying brain function and analyzing the mechanisms of neurological diseases.

Neurotransmitter Sensor Tools
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Neurotransmitter sensor tools at Creative Biolabs

Type	Fluorescent probes	Description
Dopamine Sensor	dLight/DA	Dopamine is a major neurotransmitter in the brain. Our dopamine probes include two versions: DA1h and DA1m, corresponding to high/low affinity, suitable for brain areas with different levels of dopamine release.
Glutamate Sensor	iGluSnFR	Glutamate is the major excitatory amino acid neurotransmitter in the vertebrate central nervous system. The iGluSnFR biosensor series is an important technology for the visual detection of glutamate, with signal-to-noise ratios and kinetics adequate for in vivo imaging and the ability to respond selectively to glutamate in situ.
GABA Sensor	iGABASnFR	GABA is an inhibitory neurotransmitter that regulates a variety of neurological disorders. iGABASnFR has the best performance among existing GABA sensors and is the only GABA sensor suitable for in vivo use.
Acetylcholine Sensor	Ach	Acetylcholine is the first neurotransmitter discovered and is responsible for regulating processes such as sleep, addiction, learning and memory. GACh2.0 has a high signal-to-noise ratio and high sensitivity to optical signal changes in response to physiological concentrations of acetylcholine, with sub-second kinetics and high molecular specificity.
Norepinephrine Sensor	NE	Norepinephrine is an important monoamine neurotransmitter. Our norepinephrine probes include two versions: NE1m and NE1h, corresponding to high/low affinity, suitable for detection of local synaptic transmission and non-local non-synaptic transmission of norepinephrine release.
Serotonin Sensor	5HT	5-hydroxytryptamine (5-HT), generally known as serotonin, is an essential monoamine neurotransmitter found throughout the central nervous system and peripheral tissues. Our 5-HT fluorescent probe exhibits exceptional specificity and affinity for 5-HT molecules, with reaction rates reaching sub-second levels.
GRAB Sensor	GPCR	GPCR activation-based sensors have no/low specific effects on neurons. They can be expressed in specific cell types and can detect the dynamics of extracellular neurotransmitters in cultured cells, brain slices, and living animals (e.g., flies, zebrafish, mice, rats, monkeys, etc.).

Please browse through our related products list of neurotransmitter sensors to find the right neurotransmitter tools for your experiment.

Use the list below to find the neurotransmitter sensor tools you are looking for. In addition to off-the-shelf neurotransmitter sensors, we also offer neurotransmitter sensor design and construction services. If you are interested in our services, please contact us by email and our team will get back to you as soon as possible.

For Research Use Only. Not For Clinical Use.

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