Tissue Lysates
Tissue lysates are obtained by breaking down tissue using methods such as viral, enzymatic, or osmotic lysis, resulting in a fluid containing tissue components. Tissue lysates are essential tools for researchers to study the molecular pathways involved in various diseases, such as Alzheimer's disease and Parkinson's disease. By examining the proteins present in these lysates, scientists can identify potential drug targets and develop novel treatment strategies. Tissue lysates are indispensable for advancing biomedical research and are invaluable in the quest for effective therapies.
Creative Biolabs' neural tissue lysate products span from Cytoplasmic Protein Lysates, Membrane Protein Lysates, Mitochondrial Protein Lysates, Total Protein Lysates, and Nuclear Protein Lysates. These are extracted from brains and spin cords of normal healthy or diseased human, mouse, rat and other animals with our proprietary isolation techniques. Please contact us to obtain any spot or order-to-made products of your interest.
Product Overview
Creative Biolabs is committed to delivering the following tissue lysate products from human, mouse, rat, monkey, rabbit, etc., which are ready-to-use and high quality.
Cytoplasmic Protein Lysates |
Membrane Protein Lysates |
Mitochondrial Protein Lysates |
Total Protein Lysates |
Nuclear Protein Lysates |
Customize Product |
- Cytoplasmic Protein Lysates
Cytosolic proteins are involved in regulating cell growth, maintaining intracellular environment, and carrying out essential cellular functions such as energy production and nutrient processing. Cytoplasmic protein lysates can be used for a variety of applications, including Western blotting, enzyme assays, protein-protein interaction studies, and mass spectrometry analysis.
- Membrane Protein Lysates
Membrane proteins have multiple functions and play a crucial role in cell recognition, cell signaling, transport, etc., making them excellent drug targets. The expression level of membrane proteins in organisms is low, and they have strong hydrophobic characteristics. High-quality membrane protein lysates from neural tissues empower researchers to easily identify neurological disease-specific membrane proteins.
- Mitochondrial Protein Lysates
Mitochondria are small organelles found in cells that generate energy through the process of cellular respiration. Dysfunction in mitochondria is believed to contribute to the progression of various neurodegenerative diseases in humans. Mitochondrial protein lysates can be analyzed using western blotting, mass spectrometry, or enzyme activity assays, which are becoming valuable tools for studying mitochondrial dysfunction.
- Total Protein Lysates
Total protein lysates refer to the preparation of all cellular proteins from tissues and are widely used for western blotting, protein quantification, and mass spectrometry to study the expression levels of proteins and their functions.
- Nuclear Protein Lysates
Nuclear protein lysates are cell extracts that contain proteins specifically localized in the cell nucleus. These lysates are valuable research tools for studying nuclear protein functions, interactions, and expression levels. They can be used for a variety of applications such as Western blotting, immunoprecipitation, and protein-protein interaction studies.
Applications
- Immunoassays (Western blot, ELISA…)
- Immunoprecipitation
- SDS-PAGE
- Electrophoresis
- Enzymatic Activity Analysis
Advantages
- The minimized proteolysis during preparation.
- High integrity.
- High protease activity.
- Spot stock and customized products from a range of species.
- Strain:
- Wistar Rat
- Species:
- Rat
- Tissue:
- Brain
- Tissue Site:
- Whole Brain
- Strain:
- Sprague Dawley Rat
- Species:
- Rat
- Tissue:
- Brain
- Tissue Site:
- Whole Brain
- Strain:
- BALB/c
- Species:
- Mouse
- Tissue:
- Brain
- Tissue Site:
- Whole Brain
- Strain:
- C57BL/6
- Species:
- Mouse
- Tissue:
- Brain
- Tissue Site:
- Whole Brain
- Strain:
- CD1 (ICR)
- Species:
- Mouse
- Tissue:
- Brain
- Tissue Site:
- Whole Brain
- Species:
- Human
- Tissue:
- Brain
- Tissue Site:
- Whole Brain
- Strain:
- Wistar Rat
- Species:
- Rat
- Tissue:
- Brain
- Tissue Site:
- Whole Brain
- Strain:
- Sprague Dawley Rat
- Species:
- Rat
- Tissue:
- Brain
- Tissue Site:
- Whole Brain
- Strain:
- BALB/c
- Species:
- Mouse
- Tissue:
- Brain
- Tissue Site:
- Whole Brain
- Strain:
- C57BL/6
- Species:
- Mouse
- Tissue:
- Brain
- Tissue Site:
- Whole Brain
- Strain:
- CD1 (ICR)
- Species:
- Mouse
- Tissue:
- Brain
- Tissue Site:
- Whole Brain
- Species:
- Human
- Tissue:
- Brain
- Tissue Site:
- Whole Brain
- Strain:
- Wistar Rat
- Species:
- Rat
- Tissue:
- Brain
- Tissue Site:
- Whole Brain
- Strain:
- C57BL/6
- Species:
- Mouse
- Tissue:
- Brain
- Tissue Site:
- Whole Brain
- Strain:
- CD1 (ICR)
- Species:
- Mouse
- Tissue:
- Brain
- Tissue Site:
- Whole Brain
- Species:
- Human
- Tissue:
- Brain
- Tissue Site:
- Temporal Lobe
- Species:
- Human
- Tissue:
- Brain
- Tissue Site:
- Hippocampus
- Species:
- Human
- Tissue:
- Brain
- Tissue Site:
- Amygdala
- Species:
- Human
- Tissue:
- Brain
- Tissue Site:
- Tonsilla Cerebelli
- Species:
- Human
- Tissue:
- Brain
- Tissue Site:
- Thalamus
- Species:
- Human
- Tissue:
- Brain
- Tissue Site:
- Temporal Lobe
- Species:
- Human
- Tissue:
- Brain
- Tissue Site:
- Pituitary
- Species:
- Human
- Tissue:
- Brain
- Tissue Site:
- Occipital Lobe
- Species:
- Human
- Tissue:
- Brain
- Tissue Site:
- Hippocampus
- Species:
- Human
- Tissue:
- Brain
- Tissue Site:
- Frontal Lobe
- Species:
- Human
- Tissue:
- Brain
- Tissue Site:
- Cerebral Meninges
- Species:
- Human
- Tissue:
- Brain
- Tissue Site:
- Cerebral Cortex
- Species:
- Human
- Tissue:
- Brain
- Tissue Site:
- Cerebellum
- Species:
- Human
- Tissue:
- Brain
- Tissue Site:
- Cerebellum
- Species:
- Human
- Tissue:
- Brain
- Tissue Site:
- Amygdala
- NeuroMab™ Anti-Tau Antibody(NRP-0422-P2293) (Cat#: NRP-0422-P2293)
- NeuroMab™ Anti-SEZ6 Antibody(NRP-0422-P517) (Cat#: NRP-0422-P517)
- NeuroMab™ Rabbit Anti-LRRK2 Monoclonal Antibody (CBP1887) (Cat#: NAB-08-PZ735)
- NeuroMab™ Anti-GARP Antibody(NRP-0422-P1639) (Cat#: NRP-0422-P1639)
- NeuroMab™ Anti-SEZ6 Antibody(NRP-0422-P515) (Cat#: NRP-0422-P515)
- NeuroMab™ Anti-GD2 Antibody(NRZP-1222-ZP767) (Cat#: NRZP-1222-ZP767)
- NeuroMab™ Anti-Tau Antibody(NRP-0422-P1684) (Cat#: NRP-0422-P1684)
- NeuroMab™ Anti-TREM2 Antibody(NRP-0422-P792) (Cat#: NRP-0422-P792)
- NeuroMab™ Anti-EPHB2 Antibody(NRP-0422-P1220) (Cat#: NRP-0422-P1220)
- Mouse Anti-Human α-Synuclein Phospho (Tyr39) (CBP3706) (Cat#: NAB201250LS)
- iNeu™ Human Midbrain Dopaminergic Neurons (Cat#: NCL-21P6-003)
- Mouse Microglia from C57BL/6 (Cat#: NCL-21P6-082)
- Mouse Glioma Cell Line GL-261-Luc (Cat#: NCL-2108P06)
- Human Brain Vascular Adventitial Fibroblasts (Cat#: NCL-21P6-014)
- Rat Olfactory Ensheathing Cells (Cat#: NRZP-1122-ZP162)
- C57 Brain Cortex Neurons [Mouse] (Cat#: NCC20-9PZ48)
- Green Fluorescent Tau SH-SY5Y cell Line (Cat#: NCL2110P219)
- Human Blood Brain Barrier Model (Cat#: NCL-2103-P187)
- iNeu™ Human Oligodendrocyte Progenitor Cells (OPCs) (Cat#: NCL-2103-P49)
- Sf295 Human Glioblastoma Cells (Cat#: NCL-2108P180)
- Human Tau Aggregation Kit (Cat#: NRP-0322-P2173)
- Human Poly ADP ribose polymerase,PARP Assay Kit (Cat#: NRZP-1122-ZP62)
- Alpha-Synuclein Aggregation Assay Kit (Cat#: NRZP-1122-ZP37)
- Beta Amyloid (1-40), Aggregation Kit (Cat#: NRZP-0323-ZP199)
- Beta Amyloid (1-42), Aggregation Kit (Cat#: NRZP-0323-ZP200)
- Alpha Synuclein Aggregation Kit (Cat#: NRZP-1122-ZP15)
- Human GFAP ELISA Kit [Colorimetric] (Cat#: NPP2011ZP383)
- Amyloid beta 1-42 Kit (Cat#: NRP-0322-P2170)
- AAV-mDLX-CRE-tdTomato (Cat#: NRZP-0622-ZP721)
- pAAV-syn-jGCaMP8f-WPRE (Cat#: NTA-2106-P061)
- PRV-CAG-EGFP (Cat#: NTA-2011-ZP14)
- pAAV-syn-FLEX-jGCaMP8m-WPRE (Cat#: NTA-2106-P065)
- AAV2/9-hSyn-Flpo-EGFP-WPRE-pA (Cat#: NTA-2012-ZP149)
- Dextran, Cy5 Labeled, 2000 kDa (Cat#: NRZP-0722-ZP22)
- Dextran, NHS Activated, 40 kDa (Cat#: NRZP-0722-ZP124)
- pAAV-syn-FLEX-jGCaMP8f-WPRE (Cat#: NTA-2106-P064)
- pAAV-EF1a-DIO-EGFP-WPRE (Cat#: NTA-2012AD-P285)
- pAAV-syn-jGCaMP8s-WPRE (Cat#: NTA-2106-P063)
- Human apolipoprotein E (APOE) (NM_000041) ORF clone, Untagged (Cat#: NEP-0421-R0232)
- Lenti of Human TAR DNA binding protein (TARDBP) (NM_007375) ORF clone, mGFP Tagged (Cat#: NEP-0521-R0832)
- Human huntingtin-associated protein 1 (HAP1) transcript variant 2 (NM_177977) ORF clone, Myc-DDK Tagged (Cat#: NEP-0521-R0676)
- Human presenilin 1 (PSEN1), transcript variant 2 (NM_007318) ORF clone, TurboGFP Tagged (Cat#: NEP-0421-R0140)
- App Rat amyloid beta (A4) precursor protein (App)(NM_019288) ORF clone, Untagged (Cat#: NEP-0421-R0053)
- Tau Antisense Oligonucleotide (IONIS-MAPTRx) (Cat#: NV-2106-P29)
- Human superoxide dismutase 1, soluble (SOD1) (NM_000454) ORF clone, TurboGFP Tagged (Cat#: NEP-0521-R0748)
- Human superoxide dismutase 3, extracellular (SOD3) (NM_003102) ORF clone, Untagged (Cat#: NEP-0521-R0808)
- Human huntingtin (HTT) (NM_002111) ORF clone, Myc-DDK Tagged (Cat#: NEP-0521-R0497)
- Mouse Parkinson disease (autosomal recessive, early onset) 7 (Park7) (NM_020569) clone, Untagged (Cat#: NEP-0621-R0133)
- NeuroBiologics™ Monkey Cerebrospinal Fluid (Cat#: NRZP-0822-ZP495)
- NeuroBiologics™ Pig Cerebrospinal Fluid (Cat#: NRZP-0822-ZP498)
- NeuroBiologics™ Human Cerebrospinal Fluid (Cat#: NRZP-0822-ZP491)
- NeuroBiologics™ Mouse Cerebrospinal Fluid (Cat#: NRZP-0822-ZP497)
- NeuroBiologics™ Rat Cerebrospinal Fluid (Cat#: NRZP-0822-ZP496)
- NeuroPro™ Anti-GDNF BBB Shuttle Protein (Cat#: NRZP-0423-ZP500)
- NeuroPro™ Anti-IDUA BBB Shuttle Protein (Cat#: NRZP-0423-ZP498)
- NeuroPro™ Anti-ASA BBB Shuttle Protein (Cat#: NRZP-0423-ZP504)
- NeuroPro™ Anti-SGSH BBB Shuttle Protein (Cat#: NRZP-0423-ZP505)
- NeuroPro™ Anti-TNFR BBB Shuttle Protein (Cat#: NRZP-0423-ZP510)
- NeuroPro™ Anti-PON1 BBB Shuttle Protein (Cat#: NRZP-0423-ZP507)
- NeuroPro™ Anti-EPO BBB Shuttle Protein (Cat#: NRZP-0423-ZP508)
- NeuroPro™ Anti-Erythropoietin BBB Shuttle Protein (Cat#: NRZP-0423-ZP499)
- NeuroPro™ Anti-GDNF BBB Shuttle Protein (Cat#: NRZP-0423-ZP509)
- NeuroPro™ Anti-IDUA BBB Shuttle Protein (Cat#: NRZP-0423-ZP502)