Neural Marker Antibodies
Neurons are the primary structural and functional components of the nervous system, featuring four distinct morphological components: the cell body (soma), dendrites, an axon, and presynaptic terminals. The soma is the core of cell metabolism and contains the nucleus and other organelles containing the cell's DNA. Dendrites are receivers of incoming signals. Axons generate outgoing signals. Presynaptic terminals, which contain vesicles containing neurotransmitters, are found at the ends of each axon branch. Neuronal cells are highly polarized and collect information from upstream neurons or the environment via dendritic branches, while axons send integrated information to downstream neurons or non-neuronal cells (such as muscles) via synapses.
Studying nerve cells with various functions is a vital first step in understanding how the neurological system operates. Researchers can easily identify neurons with distinct roles using antibodies targeting these neuronal markers. Additionally, researchers can:
- Examine the morphology and phenotype of neurons
- Evaluating co-localization of proteins
- Displaying synaptic connections visually
- Quantify the expression of proteins
- Determine the state of cell development
Markers of Neural Structure
Creative Biolabs provides antibodies against markers that are expressed precisely in each structural unit of neurons.
Structural Unit | Markers |
Nuclear Markers | c-Fos , FUS , HDAC1 , HDAC2 , HDAC3 , HDAC8 , NeuN , MECP2 , PCNA , STAT3 |
Soma Markers | NSE , Tyrosine Hydroxylase |
Dendrite Markers | MAP2 |
Axon Markers | Neurofilament L , Neurofilament M , Neurofilament M/H , Neurofilament H , Pan-Neurofilament, Tau |
Axon, Dendrite, and Soma Markers | α-Tubulin , β-Actin , β3-Tubulin |
Presynaptic Markers | Ankyrin-B , Cask , GRK , Snap-25 , Stonin-2 , SVOP , Synapsin , Synaptobrevin (VAMP) , Synaptophysin , Synaptotagmin-3 , Synaptotagmin-6 , Synaptotagmin-12 , Syntaxin , VGlut1 , VGlut2 , Wave1 |
Postsynaptic Markers | ADAM22 , ASIC1 , IP3R1 , Maguk , Neurogranin , PSD93 , PSD95 , SAP102 , SAP97 , SAPAP , Shank , SynDIG1 , Thorase |
Myelin Sheath Markers | Myelin Basic Protein , Myelin CNPase |
Summary of Various Neuronal Markers
We also offer reliable labeling antibodies for different kinds and stages of neurons.
Neuron Types | Markers |
Neuroepithelial cells | Nestin , SOX2 , notch1 , HES1 , HES3, E-Cadherin , occludin |
Immature neurons | Doublecortin , β3-Tubulin , NeuroD1 , TBR1 , stathmin 1 , DCX |
Mature neurons | NeuN , MAP2 , 160kDa neurofilament medium , 200kDa neurofilament heavy , synaptophysin , PSD95 |
Glutamatergic neurons | vGluT1 , vGluT2 , NMDAR1 , NMDAR2B , Glutaminase , Glutamine synthetase |
GABAergic neurons | GABA transporter 1 , GABAB receptor 1 , GABAB receptor 2 , GAD65 , GAD67 |
Dopaminergic neurons | Tyrosine Hydroxylase , Dopamine Transporter , FOXA2 , GIRK2 , Nurr1 , LMX1B |
Serotonergic neurons | Tryptophan Hydroxylase , Serotonin Transporter , Pet1 |
Cholinergic neurons | Choline Acetyltransferase , Acetylcholine Transporter , Acetylcholinesterase |
Additional Neuronal Markers | Polysialic acid-neural cell adhesion molecule (PSA-NCAM) , Neurogenic Differentiation 1 (NeuroD or Beta2) , Calbindin-D28k , Calretinin , Synaptoporin (SYNPR, SPO) |
Glial Cell Markers
Aside from the neurons that make up the central or peripheral nervous system, there is another type of non-neuronal cell called glial cells that offer structural and metabolic support to neurons. Glial cells consist of:
- NeuroMab™ Anti-Alpha Synuclein BBB Shuttle Antibody(NRZP-1022-ZP4050) (Cat#: NRZP-1022-ZP4050)
- iNeuMab™ Anti-F-Spondin/SPON1 Antibody, Clone 3F4 (Cat#: NRZP-0822-ZP4740)
- NeuroMab™ Anti-GD2 Antibody(NRZP-1222-ZP767) (Cat#: NRZP-1222-ZP767)
- NeuroMab™ Anti-Amyloid Beta 1-15 Antibody(NRP-0422-P867) (Cat#: NRP-0422-P867)
- NeuroMab™ Anti-TREM2 BBB Shuttle Antibody(NRZP-1022-ZP4114) (Cat#: NRZP-1022-ZP4114)
- NeuroMab™ Anti-Tau Antibody(NRP-0422-P1683) (Cat#: NRP-0422-P1683)
- iNeuMab™ Rabbit Anti-Alpha-synuclein (CBP1631) (Cat#: NAB-08-PZ079)
- iNeuMab™ Mouse Anti-SHANK3 Monoclonal Antibody (CBP929) (Cat#: NAB-0720-Z3477)
- Mouse Anti-Human α-Synuclein Phospho (Tyr39) (CBP3706) (Cat#: NAB201250LS)
- NeuroMab™ Anti-SEZ6 Antibody(NRP-0422-P515) (Cat#: NRP-0422-P515)
- Human Neurons Isolated from Cortex (Cat#: NCL-21P6-023)
- Human Brain Microvascular Endothelial Cells (Cat#: NCL-2103-P133)
- Human Microglia Cell Line HMC3, Immortalized (Cat#: NCL-2108P38)
- Mouse Glioma Cell Line GL-261-Luc (Cat#: NCL-2108P06)
- Rat Olfactory Ensheathing Cells (Cat#: NRZP-1122-ZP162)
- Human Brain Astroblastoma U-87 MG (Cat#: NCL2110P117)
- Mouse Retinal Ganglion Cell Line RGC-5 (Cat#: NCL2110P154)
- Human Glial (Oligodendrocytic) Hybrid Cell Line (MO3.13) (Cat#: NCL-2108P34)
- Mouse Glioma Cell Line GL261-GFP (Cat#: NCL-2108P04)
- Human Astrocytes, Immortalized (Cat#: NCL-2105-P182-AM)
- Human GFAP ELISA Kit [Colorimetric] (Cat#: NPP2011ZP383)
- Alpha-Synuclein Aggregation Assay Kit (Cat#: NRZP-1122-ZP37)
- Alpha Synuclein Aggregation Kit (Cat#: NRZP-1122-ZP15)
- Amyloid beta 1-42 Kit (Cat#: NRP-0322-P2170)
- Beta Amyloid (1-40), Aggregation Kit (Cat#: NRZP-0323-ZP199)
- Human Tau Aggregation Kit (Cat#: NRP-0322-P2173)
- Beta Amyloid (1-42), Aggregation Kit (Cat#: NRZP-0323-ZP200)
- Human Poly ADP ribose polymerase,PARP Assay Kit (Cat#: NRZP-1122-ZP62)
- pAAV-syn-FLEX-jGCaMP8f-WPRE (Cat#: NTA-2106-P064)
- pAAV-syn-jGCaMP8f-WPRE (Cat#: NTA-2106-P061)
- AAV2 Full Capsids, Reference Standards (Cat#: NTC2101070CR)
- AAV2/9-hEF1a-fDIO-eNpHR 3.0-mCherry-WPRE-pA (Cat#: NTA-2012-ZP78)
- pAAV-syn-FLEX-jGCaMP8m-WPRE (Cat#: NTA-2106-P065)
- pAAV-syn-FLEX-jGCaMP8s-WPRE (Cat#: NTA-2106-P066)
- pAAV-hSyn-DIO-XCaMP-R-WPRE (Cat#: NTA-2012AD-P508)
- VSV-eGFP (Cat#: NTA-2011-ZP20)
- Dextran, Cy5 Labeled, 2000 kDa (Cat#: NRZP-0722-ZP22)
- Dextran-FITC (Cat#: NTA-2011-ZP110)
- Human superoxide dismutase 1, soluble (SOD1) (NM_000454) ORF clone, TurboGFP Tagged (Cat#: NEP-0521-R0748)
- Human superoxide dismutase 3, extracellular (SOD3) (NM_003102) ORF clone, Untagged (Cat#: NEP-0521-R0808)
- Tau Antisense Oligonucleotide (IONIS-MAPTRx) (Cat#: NV-2106-P29)
- Lenti of Human TAR DNA binding protein (TARDBP) (NM_007375) ORF clone, mGFP Tagged (Cat#: NEP-0521-R0832)
- Lenti of Mouse synuclein, alpha (Snca) transcript variant (NM_001042451) ORF clone, mGFP Tagged (Cat#: NEP-0521-R0864)
- Mouse Parkinson disease (autosomal recessive, early onset) 7 (Park7) (NM_020569) clone, Untagged (Cat#: NEP-0621-R0133)
- Human huntingtin-associated protein 1 (HAP1) transcript variant 2 (NM_177977) ORF clone, Myc-DDK Tagged (Cat#: NEP-0521-R0676)
- ABCA1 Antisense Oligonucleotide (NV-2106-P27) (Cat#: NV-2106-P27)
- Human huntingtin (HTT) (NM_002111) ORF clone, Myc-DDK Tagged (Cat#: NEP-0521-R0497)
- Mouse SOD1 shRNA Silencing Adenovirus (Cat#: NV-2106-P14)
- NeuroBiologics™ Human Cerebrospinal Fluid (Cat#: NRZP-0822-ZP491)
- NeuroBiologics™ Rat Cerebrospinal Fluid (Cat#: NRZP-0822-ZP496)
- NeuroBiologics™ Mouse Cerebrospinal Fluid (Cat#: NRZP-0822-ZP497)
- NeuroBiologics™ Monkey Cerebrospinal Fluid (Cat#: NRZP-0822-ZP495)
- NeuroBiologics™ Pig Cerebrospinal Fluid (Cat#: NRZP-0822-ZP498)
- NeuroPro™ Anti-EPO BBB Shuttle Protein (Cat#: NRZP-0423-ZP508)
- NeuroPro™ Anti-ASA BBB Shuttle Protein (Cat#: NRZP-0423-ZP504)
- NeuroPro™ Anti-GDNF BBB Shuttle Protein (Cat#: NRZP-0423-ZP509)
- NeuroPro™ Anti-Erythropoietin BBB Shuttle Protein (Cat#: NRZP-0423-ZP499)
- NeuroPro™ Anti-SGSH BBB Shuttle Protein (Cat#: NRZP-0423-ZP505)
- NeuroPro™ Anti-IDUA BBB Shuttle Protein (Cat#: NRZP-0423-ZP498)
- NeuroPro™ Anti-IDUA BBB Shuttle Protein (Cat#: NRZP-0423-ZP502)
- NeuroPro™ Anti-NAGLU BBB Shuttle Protein (Cat#: NRZP-0423-ZP506)
- NeuroPro™ Anti-idursulfase BBB Shuttle Protein (Cat#: NRZP-0423-ZP497)
- NeuroPro™ Anti-TNFR BBB Shuttle Protein (Cat#: NRZP-0423-ZP510)