Neural Marker Antibodies
Neurons are the primary structural and functional components of the nervous system, featuring four distinct morphological components: the cell body (soma), dendrites, an axon, and presynaptic terminals. The soma is the core of cell metabolism and contains the nucleus and other organelles containing the cell's DNA. Dendrites are receivers of incoming signals. Axons generate outgoing signals. Presynaptic terminals, which contain vesicles containing neurotransmitters, are found at the ends of each axon branch. Neuronal cells are highly polarized and collect information from upstream neurons or the environment via dendritic branches, while axons send integrated information to downstream neurons or non-neuronal cells (such as muscles) via synapses.
Studying nerve cells with various functions is a vital first step in understanding how the neurological system operates. Researchers can easily identify neurons with distinct roles using antibodies targeting these neuronal markers. Additionally, researchers can:
- Examine the morphology and phenotype of neurons
- Evaluating co-localization of proteins
- Displaying synaptic connections visually
- Quantify the expression of proteins
- Determine the state of cell development
Markers of Neural Structure
Creative Biolabs provides antibodies against markers that are expressed precisely in each structural unit of neurons.
Structural Unit | Markers |
Nuclear Markers | c-Fos , FUS , HDAC1 , HDAC2 , HDAC3 , HDAC8 , NeuN , MECP2 , PCNA , STAT3 |
Soma Markers | NSE , Tyrosine Hydroxylase |
Dendrite Markers | MAP2 |
Axon Markers | Neurofilament L , Neurofilament M , Neurofilament M/H , Neurofilament H , Pan-Neurofilament, Tau |
Axon, Dendrite, and Soma Markers | α-Tubulin , β-Actin , β3-Tubulin |
Presynaptic Markers | Ankyrin-B , Cask , GRK , Snap-25 , Stonin-2 , SVOP , Synapsin , Synaptobrevin (VAMP) , Synaptophysin , Synaptotagmin-3 , Synaptotagmin-6 , Synaptotagmin-12 , Syntaxin , VGlut1 , VGlut2 , Wave1 |
Postsynaptic Markers | ADAM22 , ASIC1 , IP3R1 , Maguk , Neurogranin , PSD93 , PSD95 , SAP102 , SAP97 , SAPAP , Shank , SynDIG1 , Thorase |
Myelin Sheath Markers | Myelin Basic Protein , Myelin CNPase |
Summary of Various Neuronal Markers
We also offer reliable labeling antibodies for different kinds and stages of neurons.
Neuron Types | Markers |
Neuroepithelial cells | Nestin , SOX2 , notch1 , HES1 , HES3, E-Cadherin , occludin |
Immature neurons | Doublecortin , β3-Tubulin , NeuroD1 , TBR1 , stathmin 1 , DCX |
Mature neurons | NeuN , MAP2 , 160kDa neurofilament medium , 200kDa neurofilament heavy , synaptophysin , PSD95 |
Glutamatergic neurons | vGluT1 , vGluT2 , NMDAR1 , NMDAR2B , Glutaminase , Glutamine synthetase |
GABAergic neurons | GABA transporter 1 , GABAB receptor 1 , GABAB receptor 2 , GAD65 , GAD67 |
Dopaminergic neurons | Tyrosine Hydroxylase , Dopamine Transporter , FOXA2 , GIRK2 , Nurr1 , LMX1B |
Serotonergic neurons | Tryptophan Hydroxylase , Serotonin Transporter , Pet1 |
Cholinergic neurons | Choline Acetyltransferase , Acetylcholine Transporter , Acetylcholinesterase |
Additional Neuronal Markers | Polysialic acid-neural cell adhesion molecule (PSA-NCAM) , Neurogenic Differentiation 1 (NeuroD or Beta2) , Calbindin-D28k , Calretinin , Synaptoporin (SYNPR, SPO) |
Glial Cell Markers
Aside from the neurons that make up the central or peripheral nervous system, there is another type of non-neuronal cell called glial cells that offer structural and metabolic support to neurons. Glial cells consist of:
- iNeuMab™ Mouse Anti-EFNB2 Monoclonal Antibody (CBP1159) (Cat#: NAB-0720-Z4396)
- iNeuMab™ Anti-F-Spondin/SPON1 Antibody, Clone 3F4 (Cat#: NRZP-0822-ZP4740)
- iNeuMab™ Mouse Anti-LRP1 Monoclonal Antibody (CBP3363) (Cat#: NAB-0720-Z6479)
- Mouse Anti-SCN5A Monoclonal Antibody (CBP708) (Cat#: NAB-0720-Z2720)
- iNeuMab™ Mouse Anti-SHANK3 Monoclonal Antibody (CBP929) (Cat#: NAB-0720-Z3477)
- iNeuMab™ Rabbit Anti-Alpha-synuclein (CBP1631) (Cat#: NAB-08-PZ079)
- iNeuMab™ Rabbit Anti-LRRK2 Monoclonal Antibody (CBP1887) (Cat#: NAB-08-PZ735)
- Mouse Anti-Human α-Synuclein Phospho (Tyr39) (CBP3706) (Cat#: NAB201250LS)
- iNeu™ Human Schwann Cell (Cat#: NCL-2103-P63)
- Human Brain Astroblastoma U-87 MG (Cat#: NCL2110P117)
- Mouse Retinal Ganglion Cell Line RGC-5 (Cat#: NCL2110P154)
- Mouse Glioma Cell Line GL-261-Luc (Cat#: NCL-2108P06)
- Immortalized Human Cerebral Microvascular Endothelial Cells (Cat#: NCL-2108-P020)
- Mouse Microglia Cell Line BV-2, Immortalized (Cat#: NCL2110P153)
- iNeu™ Human Sensory Neurons (Cat#: NCL-2103-P62)
- iNeu™ Human Neural Stem Cell Line (Cat#: NCL200552ZP)
- Green Fluorescent BACE1 Cell Lines (Cat#: NCL2110P214)
- Human Blood Brain Barrier Model (Cat#: NCL-2103-P187)
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- Alpha-Synuclein Aggregation Assay Kit (Cat#: NRZP-1122-ZP37)
- Human Poly ADP ribose polymerase,PARP Assay Kit (Cat#: NRZP-1122-ZP62)
- Beta Amyloid (1-40), Aggregation Kit (Cat#: NRZP-0323-ZP199)
- Human GFAP ELISA Kit [Colorimetric] (Cat#: NPP2011ZP383)
- Human Tau Aggregation Kit (Cat#: NRP-0322-P2173)
- Alpha Synuclein Aggregation Kit (Cat#: NRZP-1122-ZP15)
- Amyloid beta 1-42 Kit (Cat#: NRP-0322-P2170)
- VSV-eGFP (Cat#: NTA-2011-ZP20)
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- Mouse SOD1 shRNA Silencing Adenovirus (Cat#: NV-2106-P14)
- Human apolipoprotein E (APOE) (NM_000041) ORF clone, Untagged (Cat#: NEP-0421-R0232)
- Human presenilin 1 (PSEN1), transcript variant 2 (NM_007318) ORF clone, TurboGFP Tagged (Cat#: NEP-0421-R0140)
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- Tau Antisense Oligonucleotide (IONIS-MAPTRx) (Cat#: NV-2106-P29)
- Lenti of Human TAR DNA binding protein (TARDBP) (NM_007375) ORF clone, mGFP Tagged (Cat#: NEP-0521-R0832)
- Human superoxide dismutase 3, extracellular (SOD3) (NM_003102) ORF clone, Untagged (Cat#: NEP-0521-R0808)
- NeuroBiologics™ Monkey Cerebrospinal Fluid (Cat#: NRZP-0822-ZP495)
- NeuroBiologics™ Rat Cerebrospinal Fluid (Cat#: NRZP-0822-ZP496)
- NeuroBiologics™ Mouse Cerebrospinal Fluid (Cat#: NRZP-0822-ZP497)
- NeuroBiologics™ Pig Cerebrospinal Fluid (Cat#: NRZP-0822-ZP498)
- NeuroBiologics™ Human Cerebrospinal Fluid (Cat#: NRZP-0822-ZP491)
- NeuroPro™ Anti-idursulfase BBB Shuttle Protein (Cat#: NRZP-0423-ZP497)
- NeuroPro™ Anti-IDUA BBB Shuttle Protein (Cat#: NRZP-0423-ZP498)
- NeuroPro™ Anti-NAGLU BBB Shuttle Protein (Cat#: NRZP-0423-ZP506)
- NeuroPro™ Anti-GDNF BBB Shuttle Protein (Cat#: NRZP-0423-ZP500)
- NeuroPro™ Anti-TNFR BBB Shuttle Protein (Cat#: NRZP-0423-ZP510)
- NeuroPro™ Anti-IDS BBB Shuttle Protein (Cat#: NRZP-0423-ZP503)
- NeuroPro™ Anti-GDNF BBB Shuttle Protein (Cat#: NRZP-0423-ZP509)
- NeuroPro™ Anti-ASA BBB Shuttle Protein (Cat#: NRZP-0423-ZP504)
- NeuroPro™ Anti-SGSH BBB Shuttle Protein (Cat#: NRZP-0423-ZP505)
- NeuroPro™ Anti-PON1 BBB Shuttle Protein (Cat#: NRZP-0423-ZP507)