Neural Cell Differentiation Kits

Human pluripotent stem cells (hPSCs), which include hESCs and hiPSCs, can self-renew and develop into three germ layers. hPSCs are extremely valuable tools for researchers investigating human nervous system development and disease. Disease-specific human neural stem cells (hNPCs) can be generated by establishing hiPSC lines from patient-derived cells.

Creative Biolabs combines research technology in the field of neuroscience to launch a complete set of neural cell acquisition and differentiation kits. It provides clients with a one-stop solution to all their neural cell acquisition and differentiation needs - convenient, fast and efficient. The cells obtained by the Neural Cell Differentiation Kits series have the typical characteristics of human neural stem cells, with normal human chromosome karyotype, high purity and high amplification capacity, and can differentiate into neurons, oligodendrocytes and astrocytes, among others. These neural cell types are significant in understanding the development and disease of the human nervous system.

Applications

Disease modeling with patient-derived iPSCs.
RNA-seq and MEA analyses of functioning neural cells.
Screening of potential drugs for the treatment of diseases.

Case Study

Disease modeling with iPSC-derived neurons is becoming a more popular alternative to investigating rodent models of neurological diseases such as epilepsy, autism, and schizophrenia.

Primary cells from neurodegenerative disease patients are collected and converted into iPSCs, which can then be differentiated into end-point cells, including motor neurons. Due to their ability to rapidly proliferate while retaining the genetic and epigenetic markers associated with neurodegenerative diseases, these cells are optimal for high-throughput screening of small molecule libraries or functional genomics-type approaches using high-content imaging or biomarker readouts.

Fig 1 Representative images of different stages of iPSC differentiation into cortical neuron cultures. (Rosa, et al., 2020) Fig. 1 iPSC differentiation into cultures of cortical neurons. Specific antibodies are used to characterize the different stages of differentiation by immunostaining.¹

At Creative Biolabs, you can solve your experimental needs in one stop. In addition to a variety of neural cell differentiation kits for you to choose from, we also provide a wide range of iPSCs and iPSC-derived cells from healthy or diseased donors.

If the product you are seeking is not currently available or if you are interested in one of our neural cell differentiation kits, please do not hesitate to contact us. Our experts will assist you in selecting the most suitable product for your specific application and help you find the ideal product for the task.

Reference

Rosa, Filip, et al. "In vitro differentiated human stem cell-derived neurons reproduce synaptic synchronicity arising during neurodevelopment." Stem Cell Reports 15.1 (2020): 22-37.

For Research Use Only. Not For Clinical Use.

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