Neural Development
In the entire neural development podcast series, we will introduce you to specific mechanisms of neural development and describe key experiments from invertebrate and vertebrate animal models. The discussion of neurodevelopmental disorders and their treatments links basic science discoveries to clinical issues in the field. We hope to help you better understand the approach to neural development. If you are interested, please follow us.
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Introduction to Developmental Neurobiology Field 00:10:23
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Origin and Development of the Nervous System 00:14:40
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Gene Regulation during Nervous System Development 00:16:08
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Neural Tissue Designation during Embryogenesis 00:09:11
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Initiation and Development of Neural Induction 00:13:57
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Noggin, Follistatin, and Chordin Inhibit Epidermal Induction 00:13:57
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The Formation of the Neural Tube 00:12:39
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Regional Division of Forebrain, Midbrain, and Hindbrain Regions 00:18:16
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Rhombomeres The Building Blocks of the Hindbrain 00:09:25
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HOX Genes Play a Crucial Role in Regulating Hindbrain Segmentation 00:16:34
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How are Retinoic Acid Levels Controlled 00:09:45
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Anatomical Landmarks and Signaling Centers in the Posterior Vertebrate Neural Tube 00:08:51
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Ventral Signals and Motor Neuron Patterning in the Posterior Neural Tube 00:16:59
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Dorsal Patterning in the Posterior Neural Tube 00:13:20
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Regulatory Signaling Pathways in Dorsal Neuron Development 00:13:20
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How Dorsal Ventral Patterning Works in the Front of the Neural Tube 00:15:42
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The Process of Generating Neurons and Glial Cells 00:16:40
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Cellular Migration in the Central Nervous System 00:16:35
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Mechanisms of Neuronal Migration 00:13:36
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Migration Patterns of Neurons 00:14:46
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Migration in the Peripheral Nervous System Examples from Neural Crest Cells 00:15:36
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Lateral Inhibition and Notch Receptor Signaling 00:16:34
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Exploring the Mechanisms of Fate Determination in Vertebrate Central Nervous System Neurons 00:13:18
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Determination and Differentiation of Neural Crest-Derived Neurons 00:13:18
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The Role of Neuregulin in the Determination of Myelinating Schwann Cells in the Peripheral Nervous System 00:15:04
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Development of Specialized Sensory Cells 00:12:54
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Development of the Inner Ear and Retina in Vertebrates 00:14:20
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Development of Specialized Sensory Cells 00:12:05
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Growth Cone Motility and Pathfinding 00:14:58
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Growth Cone Substrate Preferences In Vitro and In Vivo 00:15:09
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Guidance Mechanisms in Vertebrate Motor Neuron Development 00:13:27
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Guidance Mechanisms for Commissural Axons Attraction and Repulsion at the Midline 00:16:59
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Regulatory Mechanisms of Commissural Axon Growth in Vertebrates 00:11:47
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The Retinotectal System and the Chemotopy Hypothesis 00:14:05
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Advances in Retinal Axon Guidance Chemoaffinity, Eph-Ephrin, and Self-Avoidance 00:13:07
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Nerve Cell Development Insights from Tissue Size, Tumors, and In Vitro Studies 00:14:52
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Discovery and Identification of Nerve Growth Factor and Related Neurotrophic Proteins 00:16:32
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Neurotrophin Signaling and Trk Receptor Function in Cell Survival and Transport 00:17:40
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Trk Receptor Interactions and Growth Factor Signaling in Neuronal Survival and Outgrowth 00:16:46
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Programmed Cell Death During Neural Development 00:18:06
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p75NTR and Precursor Forms of Neurotrophins Help Mediate Neuronal Death During Development 00:15:03
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Chemical Synapse Development in the Peripheral and Central Nervous Systems 00:10:24
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Development and Organization of the Neuromuscular Junction 00:15:48
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Revised Agrin Hypothesis Synaptic Basal Lamina and ACh Receptor Clustering 00:16:53
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MuSK, LRP4, and Rapsyn Mediate Agrin Signaling and AChR-Cytoskeleton Linkage 00:15:11
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Roles of Nerve-Adjacent Nuclei, Schwann Cells, and Basal Lamina in Neuromuscular Junction Formation and Maintenance 00:16:38
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Synaptic Basal Lamina and Laminins in Presynaptic Development 00:10:21
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Models of Synaptic Elimination in the Neuromuscular Junction 00:14:12
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Similarities in Synaptic Elements and the Role of Postsynaptic Density 00:17:43
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Cell Adhesion Molecules, Neurexins, and Neuroligins in Synaptic Stabilization 00:17:23
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Reciprocal Signaling and the Role of Motile Dendritic Spines in Synaptic Development 00:14:08
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BDNF and EphEphrin Signaling in Synaptic Development 00:16:52
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Regulation of Synaptic Formation EphEphrin and Wnt Signaling in the CNS 00:14:33
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Wnt Pathways and Glial Cells in Synaptogenesis at Excitatory and Inhibitory Synapses 00:15:24
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Exploring Synapse Elimination, Reorganization, and Retinal Activity in the Vertebrate Visual System 00:13:51
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Neural Competition and Visual Experience in Ocular Dominance and Synaptic Organization 00:13:07
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Homeostatic Plasticity and Lifelong Synaptic Organization 00:16:40
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