Mouse Anti-PFN1 Monoclonal Antibody (CBP6810)
[CAT#: NAB2007FY1759]
Amyotrophic Lateral Sclerosis,
Parkinson's, Alzheimer's and Huntington's diseases
- Host Species:
- Mouse
- Species Reactivity:
- Human
- Applications:
- IHC; WB
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To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
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SPECIFIC INQUIRY
inquiryProduct Overview
Description
Neurodegenerative diseases, such as amyotrophic lateral sclerosis, Parkinson's disease, Alzheimer's disease and Huntington's disease The result of the gradual loss of neuron structure and function, Causes neuron death. Profilin-1 is a protein encoded by the PFN1 gene in humans. The protein encoded by this gene is a ubiquitous actin monomer binding protein belonging to the profilin family. It is thought to regulate actin polymerization in response to extracellular signals. The deletion of this gene is related to Miller-Dieker syndrome. Mutations in this gene may be a rare cause of amyotrophic lateral sclerosis (also known as Lou Gehrig's disease).
Species Reactivity
Human
Clonality
Monoclonal
Host Species
Mouse
Isotype
IgG2a
Clone Number
CBP6810
Applications
IHC; WB
Application Notes
IHC: 1:1000-1:2500
WB: 1 µg/ml
WB: 1 µg/ml
Relevant Diseases
Alzheimer's Disease; Huntington's Disease; Parkinson's Disease; Amyotrophic Lateral Sclerosis
Product Properties
Form
Liquid
Formulation
PBS, pH 7.2, 40% glycerol
Preservatives
0.02% Sodium azide
Concentration
0.5 mg/ml
Purification
Protein A purified
Shipping
Gel Pack
Storage
Store at +4°C for short term storage. Long time storage is recommended at -20°C.
Handling Advice
The antibody solution should be gently mixed before use.
Research Use Only
For research use only
Target
Publications
Publications (0)
Neural Antibodies
For Research Use Only. Not For Clinical Use.
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