NeuroMab™ Anti-Delta GABA-A receptor BBB Shuttle Antibody, Clone N151/3

[CAT#: NRZP-0423-ZP117]

Species Reactivity:: Rat; Mouse

Applications:: WB; IHC; ICC

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Product Overview

Description

The BBB is a highly selective membrane that surrounds the blood vessels in the brain, and it can prevent many molecules, including potentially life-saving drugs, from entering the brain. The anti-GABRD BBB Shuttle Antibody is designed to bind to receptors on the surface of cells in the BBB, and once bound, the antibody can cross the BBB and into the brain. This technology has the potential to revolutionize the treatment of brain disorders by enabling drugs to reach the brain more effectively.

Immunogen

Synthetic peptide amino acids 15-34 (CTQPHHGARAMNDIGDYVGS, extracellular N-terminus) of rat GABA-A-R-Delta (also known as gamma-aminobutyric acid receptor subunit delta, accession number P18506)
Mouse: 100% identity (20/20 amino acids identical)
Human: 75% identity (15/20 amino acids identical)

Construction

We offer several options for BBB shuttle antibody design. Antibody construction can be customized according to customer requirements.

Species Reactivity

Rat; Mouse

Clonality

Monoclonal

Isotype

IgG2a

Clone Number

N151/3

Applications

WB; IHC; ICC

Conjugation

Unconjugated

Product Properties

Research Use Only

For reseaech use only, not for human or dignostic use.

Target

GABRD

Official Name

GABRD

Full Name

GABA(A)R, Delta

Alternative Names

Gamma-Aminobutyric Acid Type A Receptor Delta Subunit; Gamma-Aminobutyric Acid (GABA) A Receptor; Delta; GABA(A) Receptor Subunit Delta; GABA(A) Receptor; Delta; Gamma-Aminobutyric Acid Receptor Subunit Delta; GABA-A Receptor; Delta Polypeptide; GEFSP5; EIG10; EJM7;