Dextran, NHS Activated

Product Overview

Description

Dextrans are hydrophilic polysaccharides characterized by their moderate-to-high molecular weight (3-200 kD). These molecules can exist in either charged or uncharged forms depending on the conjugated fluorophore. Due to their low immunogenic properties, dextrans are often used as effective tracers in various applications.

Tracer Type

Dextan Conjugate

Applications

Neural Tracing

Research Areas

Neural Circuit Mapping

Properites

Standard Filter Set

Dextran

Soluble In

Water

Appearance

powder

Shipping

Blue ice

Storage

-20°C, Protect from moisture

Research Use Only

For research use only.

Publications

Publications (0)

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Scientific Resources

[Hot Topics]

An Overview of Probes for Neuroscience Research

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Customer Reviews and Q&As

Customer Reviews Average Customer Ratings Overall

5.0

Excellent

The product consistently provides clear and reliable labeling of neural pathways

The 40 kDa size is perfect for our experiments, allowing for excellent penetration and minimal background staining. It's easy to work with and the results are reproducible, which is crucial for our research. Highly recommend for anyone in the neurobiology field.

Excellent

Ideal for our experiments involving neural tracing

It ensures precise labeling with minimal diffusion, which is exactly what we need for our high-resolution imaging studies. The product quality is excellent, and we've experienced consistent performance across multiple batches. This is definitely our go-to reagent for neural tracing.

Excellent

The product provides strong, consistent labeling and is easy to use

We've been able to trace complex neural pathways with greater clarity than with other products we've tried. It's reliable and efficient, making it an essential part of our toolkit.

Excellent

We've been very impressed with the performance of Dextran

Highly recommended for anyone conducting similar research. The labeling is bright and specific, which is crucial for our detailed analyses of neural circuits. The product is easy to handle, and the instructions are clear, making the entire process seamless.

Excellent

This product is essential for our neuroanatomical research

Our lab has been using Dextran, and it has exceeded our expectations. The product's performance is reliable, providing clear and distinct labeling of neural pathways. It's easy to use, and we've obtained reproducible results every time.

Q&As

What methods are recommended for conjugating Dextran, NHS Activated with fluorescent dyes or proteins?

To conjugate Dextran, NHS Activated with fluorescent dyes or proteins, follow a standard NHS-ester coupling protocol. Mix the Dextran with the dye or protein in a suitable buffer, typically under mild conditions to avoid degradation. It's important to optimize the reaction conditions, such as pH and temperature, to ensure efficient conjugation and minimal byproducts.

How stable is Dextran, NHS Activated once it is conjugated with a fluorescent dye?

Once conjugated, Dextran, NHS Activated generally exhibits good stability, provided that it is stored and handled correctly. The conjugated product should be stored at recommended temperatures, protected from light, and used within the suggested time frame to ensure optimal performance. Stability can also be affected by the specific dye or protein used, so it's important to consult specific protocols for each conjugation.

Are there any specific storage requirements for Dextran, NHS Activated to maintain its efficacy?

Dextran, NHS Activated should be stored according to the recommendations, typically in a cool, dry place, and protected from light. It is often advisable to store it at -20°C or lower to maintain its stability. Avoid repeated freeze-thaw cycles, as they can affect the integrity of the tracer. Always consult the product's datasheet for detailed storage instructions.