NeuroMab™ Anti-Tau Antibody(NRP-0422-P1684)

Product Overview

Description

The monoclonal antibody has attached itself to both humans and rhesus macaque tau proteins. It can effectively impede the aggregation of tau proteins.

Immunogen

NRP-0422-P1684 monoclonal antibody recognize only human tau at the N-terminal region (epitope at residues 25-30 aa).

Species Reactivity

Human

Clonality

Monoclonal

Host Species

Mouse

Applications

FC; ELISA; Inhib; In Vitro; In Vivo

Relevant Diseases

Alzheimer's Disease

Product Properties

Formulation

PBS only

Preservatives

BSA Free

Concentration

1mg/mL

Purification

Purified recombinant IgG prepared by affinity chromatography on Protein A from a mammalian cell line

Purity

> 95% (SDS-PAGE)

Endotoxin Level

Regular Endotoxin < 5 EU/mg
Low Endotoxin < 1 EU/mg

Shipping

Gel Packs

Storage

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Research Use Only

For research use only

Target

Tau

Official Name

Tau

Full Name

Tau

Alternative Names

CD14

Gene ID

4137(Human); 17762(Mouse); 29477(Rat)

Uniprot ID

P10636(Human); P10637(Mouse); P19332(Rat)

Publications

Publications (0)

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Kits

Human Tau proteins ELISA kit

Total Tau Cellular Kit

Human Tau ELISA Kit [Colorimetric]

Cleaved Tau ELISA Kit (Human Asp738/Mouse Asp713) [Colorimetric]

Human Tau ELISA Kit [Colorimetric], One-Step Assay

Cleaved Tau Antibody Pair, BSA and Azide Free (Human Asp738/Mouse Asp713)

Human Tau Aggregation Kit

Tau / MAPT ELISA Kit, Human

MAP-Tau Kit

Human Tau ELISA Kit, Fluorescent [Fluorescent]

Neural Cell Lines

Tau Phosphorylation Assay Cell Line

Neural Genes

Mouse microtubule-associated protein tau (Mapt) transcript variant 2 (NM_010838) ORF clone/Lentiviral Particle, Untagged

Mouse microtubule-associated protein tau (Mapt) transcript variant 3 (NM_001285454) ORF clone, Untagged

Mouse microtubule-associated protein tau (Mapt) transcript variant 5 (NM_001285456) ORF clone, Untagged

Homo sapiens microtubule-associated protein tau (MAPT) transcript variant 7 (NM_001203251) ORF clone, Untagged

Homo sapiens microtubule-associated protein tau (MAPT) transcript variant 8 (NM_001203252) ORF clone, Untagged

Homo sapiens microtubule-associated protein tau (MAPT) transcript variant 7 (NM_001203251) ORF clone, Myc-DDK Tagged

Mouse microtubule-associated protein tau (Mapt) transcript variant 4 (NM_001285455) ORF clone/Lentiviral Particle, Untagged

Mouse microtubule-associated protein tau (Mapt) transcript variant 1 (NM_001038609) ORF clone, Untagged

Tau Antisense Oligonucleotide (IONIS-MAPTRx)

Rat microtubule-associated protein tau (Mapt) (NM_017212) ORF clone, Untagged

Scientific Resources

[Brochure]

Neuros Antibody Product Panel

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Customer Reviews and Q&As

Customer Reviews Average Customer Ratings Overall

5.0

Excellent

This feature is particularly useful for our research

We used it successfully in both FC and ELISA assays to track Tau protein levels. The results were consistent and reproducible, providing valuable insights into Tau pathology.

Excellent

A valuable addition to our toolkit

I was impressed with how well this antibody performed in our in vitro assays. It showed high specificity for Tau proteins and minimal cross-reactivity, which is crucial for our studies on Tau phosphorylation.

Excellent

Facilitated our analysis of Tau aggregation

The antibody's performance in various assays has helped us understand Tau-related neurodegenerative diseases better.

Excellent

Strong performance with minimal background

We found this antibody excellent for our FC experiments. It provided clear, distinct staining with minimal background noise, allowing us to accurately analyze Tau protein expression in our samples.

Excellent

Delivered consistent, high-quality results

The antibody worked exceptionally well in our ELISA assays. We obtained high signal-to-noise ratios and reproducible results across multiple experiments, which was critical for our quantitative analysis

Q&As

Are there any recommended protocols for using this antibody in Flow Cytometry?

For Flow Cytometry, we recommend using a staining buffer and optimizing the antibody concentration to achieve the best signal-to-noise ratio. It is advisable to include appropriate controls and validate the staining protocol for your specific cell types and experimental conditions.

Can this antibody be used to detect different Tau isoforms?

NRP-0422-P1684 monoclonal antibody recognize only human tau at the N-terminal region (epitope at residues 25-30 aa). It is important to check the specific binding characteristics and ensure it matches your experimental requirements

Is this antibody suitable for use in in vivo studies?

Yes, the antibody is suitable for in vivo studies. It has been successfully used in animal models to study Tau protein localization and function, providing valuable insights into Tau's role in neurodegenerative diseases.