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Creative Biolabs

NeuroMab™ Anti-LRRK2/Dardarin-pSer910 BBB Shuttle Antibody, Clone 1D8

[CAT#: NRZP-0423-ZP252]

Species Reactivity:
Human; Mouse
Applications:
ELISA; DB; ICC; WB

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Product Overview

Description

The BBB is a highly selective membrane that surrounds the blood vessels in the brain, and it can prevent many molecules, including potentially life-saving drugs, from entering the brain. The anti-LRRK2 BBB Shuttle Antibody is designed to bind to receptors on the surface of cells in the BBB, and once bound, the antibody can cross the BBB and into the brain. This technology has the potential to revolutionize the treatment of brain disorders by enabling drugs to reach the brain more effectively.

Immunogen

Synthetic peptide amino acids 904-917 (VKKKSN[pS]ISVGEFY) of human LRRK2 (also known as Leucine-rich repeat serine/threonine-protein kinase 2, Dardarin and PARK8, accession number Q5S007)
Mouse: 85% identity (12/14 amino acids identical)
Rat: 85% identity (12/14 amino acids identical)

Construction

We offer several options for BBB shuttle antibody design. Antibody construction can be customized according to customer requirements.

Species Reactivity

Human; Mouse

Clonality

Monoclonal

Isotype

IgG2a

Clone Number

1D8

Applications

ELISA; DB; ICC; WB

Conjugation

Unconjugated
Product Properties

Research Use Only

For reseaech use only, not for human or dignostic use.
Target

Target

LRRK2

Official Name

LRRK2

Full Name

LRRK2/Dardarin-pSer910

Alternative Names

LRRK2; AURA17; DARDARIN; PARK8; RIPK7; ROCO2; leucine-rich repeat kinase 2; leucine rich repeat kinase 2

Uniprot ID

Q5S007
Publications

Publications (0)

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