NeuroMab™ Anti-VGlut2 BBB Shuttle Antibody, Clone N29/29
[CAT#: NRZP-0423-ZP464]
- Species Reactivity:
- Rat; Mouse
- Applications:
- WB; IHC; ICC
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To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
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SPECIFIC INQUIRY
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Description
The BBB is a highly selective membrane that surrounds the blood vessels in the brain, and it can prevent many molecules, including potentially life-saving drugs, from entering the brain. The anti-VGLUT2 BBB Shuttle Antibody is designed to bind to receptors on the surface of cells in the BBB, and once bound, the antibody can cross the BBB and into the brain. This technology has the potential to revolutionize the treatment of brain disorders by enabling drugs to reach the brain more effectively.
Immunogen
Fusion protein amino acids 501-582 (cytoplasmic C-terminus) of rat VGlut2 (also known as Vesicular glutamate transporter 2, Differentiation-associated BNPI, Differentiation-associated Na(+)-dependent inorganic phosphate cotransporter, Dnpi, Solute carrier family 17 member 6 and Slc17a6, accession number Q9JI12)
Mouse: 97% identity (80/82 amino acids identical)
Human: 89% identity (73/82 amino acids identical)
<50% identity with VGlut1 or VGlut3
Mouse: 97% identity (80/82 amino acids identical)
Human: 89% identity (73/82 amino acids identical)
<50% identity with VGlut1 or VGlut3
Construction
We offer several options for BBB shuttle antibody design. Antibody construction can be customized according to customer requirements.
Species Reactivity
Rat; Mouse
Clonality
Monoclonal
Isotype
IgG1
Clone Number
N29/29
Applications
WB; IHC; ICC
Application Notes
Does not cross-react with VGlut1 or VGlut3
Research Areas
Transporters
Conjugation
Unconjugated
Product Properties
Research Use Only
For reseaech use only, not for human or dignostic use.
Target
Target
VGLUT2
Official Name
SLC17A6
Full Name
VGlut2
Alternative Names
Vesicular glutamate transporter 2
Uniprot ID
Q9JI12
Publications
Publications (0)
Neural Antibodies
For Research Use Only. Not For Clinical Use.
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