AAV2/2Retro-CAG-DIO-EGFP-2A-TetTox-pA [Neural Tracing]

[CAT#: NTA-2012-ZP303]

Tracer Type:: Neuronal Synaptic Depression

Applications:: Neural Tracing

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Product Overview

Description

The CAG promoter is a combination of the CMV promoter (C), the chicken β-actin intron (A) and the rabbit β-globin intron region (G). It is a constitutive promoter with a strong promoter and has no cell tissue specificity.

TetTox, also known as TeNT, is the light chain of Tetanus toxin. It is a protease that can specifically degrade VAMP2, inhibit the release of synaptic glutamate transmitter vesicles, and interrupt the transmission of nerve electrical signals.

EGFP, green fluorescent protein, excitation wavelength 488nm, emission wavelength 507nm.