NeuroMab™ Anti-KChIP1 potassium channel BBB Shuttle Antibody, Clone K55/7
[CAT#: NRZP-0423-ZP184]
- Species Reactivity:
- Rat; Mouse; Human
- Applications:
- WB; IHC; IP; ICC
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To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
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SPECIFIC INQUIRY
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Description
The BBB is a highly selective membrane that surrounds the blood vessels in the brain, and it can prevent many molecules, including potentially life-saving drugs, from entering the brain. The anti-KCNIP1 BBB Shuttle Antibody is designed to bind to receptors on the surface of cells in the BBB, and once bound, the antibody can cross the BBB and into the brain. This technology has the potential to revolutionize the treatment of brain disorders by enabling drugs to reach the brain more effectively.
Immunogen
Fusion protein amino acids 1-227 (full-length) of rat KChIP1b (also known as Kcnip1, Kv channelinteracting protein 1, Potassium channel-interacting protein 1, A-type potassium channel modulatory protein 1, Vesicle APC-binding protein and VABP, accession number Q8R426)
Mouse: 99% identity (226/227 amino acids identical)
Human: 99% identity (225/227 amino acids identical)
>50% identity with KChIP2, KChIP3 and KChIP4
Mouse: 99% identity (226/227 amino acids identical)
Human: 99% identity (225/227 amino acids identical)
>50% identity with KChIP2, KChIP3 and KChIP4
Construction
We offer several options for BBB shuttle antibody design. Antibody construction can be customized according to customer requirements.
Species Reactivity
Rat; Mouse; Human
Clonality
Monoclonal
Isotype
IgG1
Clone Number
K55/7
Applications
WB; IHC; IP; ICC
Application Notes
Does not cross-react with KChIP2, KChIP3 or KChIP4
Research Areas
K+ channels
Conjugation
Unconjugated
Product Properties
Research Use Only
For reseaech use only, not for human or dignostic use.
Target
Target
KCNIP1
Official Name
KCNIP1
Full Name
KChIP1 K+ channel
Alternative Names
VABP; KCHIP1
Uniprot ID
Q8R426
Publications
Publications (0)
Neural Genes
Neural Antibodies
For Research Use Only. Not For Clinical Use.
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